Abbreviations
In this guide
In this guideThis is a discussion paper. It does not reflect the views of the Committee. It should not be cited.
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AESAN |
Spanish Scientific Committee of the Spanish Agency for Food Safety and Nutrition |
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AhR |
Aryl hydrocarbon receptor |
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AIDS |
Acquired immune deficiency syndrome |
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ALP |
alkaline phosphatase |
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ALT |
Alanine transaminase |
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ANA |
Anti-nuclear antibody |
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ANSES |
French Agency for Food, Environmental and Occupational Health and Safety |
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ANSM |
French National Agency for the Safety of Medicines and Health Products |
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ASMA |
Anti-smooth muscle antibodies |
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ASP |
Aspartate aminotransferase |
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ATP |
Adenosinetriphosphate |
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BaP |
Benzo[a]pyrene |
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BMI |
Body mass index |
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CHO |
Chinese hamster ovary cell line |
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COT |
Committee on the Toxicity of Chemicals in Food, Consumer Products and the Environment |
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CYP |
Cytochrome P450 |
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DCFH-DA |
2′− 7′- dichlorodihydrofluorescein diacetate |
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DGCCRF |
General Directorate for Competition, Consumer Affairs and Fraud Control |
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DILIN |
US Drug Induced Liver Injury Network |
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DMSO |
Dimethyl sulfoxide |
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EAT |
Exposure assessment team |
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FSA |
Food Standards Agency |
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FSS |
Food Standards Scotland |
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GGT |
Gamma-glutamyl transferase |
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HCA |
Hydroxycitric acid |
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HDS |
Herbal and dietary supplements |
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HepG2 |
Hepatocellular carcinoma cell line |
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HIV |
Human immunodeficiency virus |
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IC50 |
Half maximal inhibitory concentration |
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IPS |
Italian Phytovigilance System |
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LATINDILI |
Latin America-Drug Induced Liver Injury database |
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MDCK-MDR1 |
Madin-Darby Canine Kidney-Human Multidrug Resistance gene-1 cell line |
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MHRA |
Medicines and Healthcare products Regulatory Agency |
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MIDS |
Multi-ingredient dietary supplements |
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MMC |
Mitomycin C |
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MNPCE |
Micronucleated polychromatic erythrocytes |
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MTT |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide |
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NCE |
Normochromatic erythrocytes |
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NDNS |
National Diet and Nutrition Survey |
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NOAEL |
No observed adverse effect level |
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PXR |
Pregnane X receptor |
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RCT |
Randomised clinical trial |
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ROS |
Reactive oxygen species |
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TB |
Total bilirubin |
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TGA |
Australian Department of Health, Disability and Ageing Therapeutic Goods Administration |
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UK |
United Kingdom |
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US FDA |
United States Food and Drug Administration |
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US NCCIH |
United States National Centre for Complementary and Integrative Health |
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WG |
Working Group |
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WHO |
World Health Organisation |