COT/COM/COC Annual Report Index

I - Index

Last updated: 11 January 2024

Subject:

Idiopathic Environmental Intolerance: Evidence for a toxicological mechanism

Year

Page

and psychological aspects of IEI

2010

27

reviewed the published scientific literature on

2011

13

Idiopathic Environmental Intolerance: Evidence for a toxicological mechanism

2009

36

Subject:

IGHRC

Year

Page

paper on uncertainty factors

2001

13

paper on uncertainty factors

2002

129

Guidance document on chemical mixtures

2007

21

Guidelines on route-to-route extrapolation of toxicity data when assessing health risks of chemicals

2005

15

Subject:

IGF-1: Possible carcinogenic hazard to consumers IGF-1 and cancer risk

Year

Page

dietary absorption, levels of IGF-1in food and the association between blood levels of IGF1 and the risk of certain types of cancer.

2012

47

dietary absorption, levels of IGF-1 in food and the association between blood levels of IGF1 and the risk of certain types of cancer. The review is ongoing, though it was not possible to progress work on it in 2013.

2013

58

dietary absorption, levels of IGF-1 in food and the association between blood levels of IGF-1 and the risk of certain types of cancer.

2017

55

Insulin-like growth factor-1 (IGF-1) in the diet, The potential  carcinogenic risk of

2009

229

Subject:

ILSI/HESI

Year

Page

ILSI/HESI research programme on alternative cancer models: results of Syrian hamster embryo cell transformation assay

2002

87

ILSI/HESI workshop on less-than-lifetime exposure to carcinogens

2012

44

Subject:

Imidocarb (antiparasitic drug used to treat babesiosis in cattle)

Year

Page

Safety of,

1992

38, 57

Subject:

Impurities

Year

Page

determining, testing, controlling specific impurities in pharmaceuticals that possess potential for genotoxicity.

2008

227

Genotoxicity Testing of Impurities

2011

44

in the pesticide 1-methylcyclopropene

2003

191

Interim Guidance on a Strategy for Genotoxicity Testing and  Assessment of Impurities

2012

35

Testing strategies for impurities, COM update on guidance

2021

54

Subject:

Immunomodulation in cancer development

Year

Page

Immunological and stromal cell modulations relevant to cancer, presentation to COC

2018

50

Subject:

Intrahepatic cholangiocarcinoma

Year

Page

Increase in mortality rates from intrahepatic cholangiocarcinoma in England and Wales 1968-1998

2001

138

Intrahepatic cholangiocarcinoma

2003

192

Subject:

In the diet of infants and children

Year

Page

contaminants in- overarching statement. 

2019

8

Hydrolysed cows’ milk formulae: role in influencing the development of atopic outcomes and autoimmune disease

2016

14

Statement on the potential risk from chemicals in the diet of infants aged 0 to 12 months and children aged 1 to 5 years.

2020

9

Health assessment of the exposure of 2 year-olds to chemical substances in consumer products’  Danish Environmental Protection Agency (EPA) report on

2010

8

Infant feeding and allergy

2013

30

Infant food, metals and other elements in

1999

27

Iodine in the diet of infants and young children

2017

7

Long chain polyunsaturated fatty acid for use in infant formula

1997

19

Methylmercury in the diets of infants and young children

2018

8

Neosolaniol, T2-toxin and HT2-toxin in the diet of infants aged 0-1 and young children aged 1-5 years. 

2018

15

Effect of certain food colours and a preservative on behaviour in children research project results

2007

8

Oat drinks in the diet of infants aged 1-5

2019

19

Oat drinks in the diet of infants aged 1-5

2020

29

Endosulfan, pentachlorobenzene and chlordecone in the infant diet

2013

18

Phthalates in infant formulae

1996

10

Phytoestrogens in soya-based infant formulae

1998

17,18

Phytoestrogens in soya-based infant formulas

1999

35

Polybrominated biphenyls (PBBs) in diet of infants

2015

9

Polybrominated biphenyls (PBBs) in diet of infants and 1 – 5

year old children

2015

10

Soya drinks, in the diet of infants aged 1-5

2019

19

Soya drinks, in the diet of infants aged 1-5

2020

29

T2-toxin and HT2-toxin and neosolaniol in the diet of infants aged 0-1 and young children aged 1-5 years. 

2018

15

Subject:

In vitro micronucleus test

Year

Page

COM considered the progress in the development of the

1994

26

European Environmental Mutagenicity Society (EEMS)

1996

47

COM advice and evaluation of

2004

144

(IWGT meeting)

2002

88

Subject:

In vivo assays

Year

Page

In vivo gene mutation assays using transgenic animal mode models

1996

45

In-vivo mutagenicity at high doses, Significance of

2002

89

In vivo PIG-A mutagenicity assay

2010

44

Subject:

Iodine

Year

Page

Toxicity in adults and young children

1992

25

Fluorine and bromine, 1997 Total Diet Study

2000

17

in cows’ milk

Year

Page

Iodine

1997

17

Iodine

1999

20

Iodine

2002

20

Iodine

2003

10

in diet of infants and young children

2017

7

Potential effects of excess iodine intake during preconception, pregnancy and lactation, statement on

2020

19

ongoing work on the COT contribution to the SACN risk assessment on nutrition and,

2021

34

Subject:

Iron

Year

Page

Iron, Toxicological aspects of the SACN report on

2009

29

report on Iron and Health,

2009

75

Subject:

Irritant Sprays

Year

Page

Irritant sprays

2016

14

Guidance on submission of papers to COT regarding irritant sprays and information required

Year

Page

Guidance to applicants on the type of information that should be supplied to enable the Committee to develop an opinion about the safety of the formulation.

2017

28

Home Office Centre for Applied Science and Technology (now Dstl) requests review of the safety of these from the COT.

2018

16