COT/COM/COC Annual Report Index

C - Index

Last updated: 11 January 2024

Subject :

Cadmium,

Year

Page

in the 2006 Total Diet Study in the infant diet

2009

12

establishing a revised Tolerable Weekly Intake (TWI)

2009

12

Comparing exposure to the TWI established in 2009

2018

9

ongoing work on the COT contribution to the SACN risk assessment on nutrition and, cadmium

2021

31

Subject:

Caffeine

Year

Page

Caffeine and alcohol: combined effects on health and behaviour

2012

7

EFSA consultation on a draft scientific opinion on the safety of caffeine

2015

7

Reproductive effects of

2001

22

Reproductive effects of

2007

24

Reproductive effects of

2008

14, 49

Subject:

Calcium-parathyroid hormone axis

Year

Page

Phosphate and the,

2004

11, 54

Subject:

Cancer

Year

Page

Oesophageal cancer

2004

178

The role of miRNA related effects and chemicals on cancer

2011

56

Subject:

Cancer aetiology

Year

Page

and causal inference.

2017

53

Subject:

Cancer incidence near municipal solid waste

incinerators

Year

Page

in Great Britain

2000

104

Update review of epidemiological studies on

2008

284

Review of

2009

240

Subject:

Cancer risk

Year

Page

DNA adducts as a biomarker for

2008

277

Joint COC/COM symposium on genetic susceptibility to cancer

1998

35

Epidemiological data linking cancer and alcohol

1995

58

Modification of, COC discussion of

2021

76

Subject:

Cannabidiol (CBD)

Year

Page

Cosmetic products, potential risks from use of topically applied CBD-containing

2020

28

COT review of,

2019

16, 36

Genotoxicity of, COM evaluation

2020

50

Inhalation, potential adverse effects associated with exposure to CBD) by

2020

28

Position paper on CBD in food products

2020

11

Updated position paper on

2021

24

Subject:

Canned foods

Year

Page

Bisphenol A in

2001

8

Subject:

Captan (fungicide)

Year

Page

COM and COC Evaluation of

1993

35, 50

Subject:

Caramel (Type 1)

Year

Page

Evaluation of

1991

30

Subject:

Carbaryl

Year

Page

COM and COC Evaluation of

1995

30, 64

Subject:

Carbon nanotubes

Year

Page

Carcinogenicity of

2010

60

Carcinogenicity of

2011

58

Subject:

Carcinogenesis

Year

Page

age-related differences in susceptibility to

2006

281

mode of action / human relevance framework

2005

134

mode of action / human Relevance Framework

2008

279

“Tissue Organisation Field Theory” of

2006

286

Carcinogenic air pollutants, Quantification of risk

2002

128

Carcinogenicity guidelines

1991

44

Subject:

Carcinogens

Year

Page

COC guidance on a strategy for the risk assessment of

2004

188

Assessing the risks of acute or short-term exposure to

2007

179

Early life exposure-  assessing susceptibility from EPA risk assessment guideline: supplemental data for

2003

195

Guidance Statements on the risk assessment of

2010

63

Occupational, HSE priority programme

2004

177

Insulin-like growth factor-1 (IGF-1) in the diet, The potential  carcinogenic risk of

2009

78

Interaction between genotype and chemicals in the environment on the induction of cancer in risk assessment

2011

53

Risk assessment of carcinogens, Revised guidance

2003

197

COC guidance on a strategy for the risk assessment of carcinogens

2004

188

Single or short term exposure to carcinogens

2005

140

Use of target organ mutagenicity data in carcinogen risk assessment

2005

124

Organ mutagencity data in carcinogen risk assessment

2005

124

Subject:

Carcinogenicity

Year

Page

Chemical carcinogenicity revisited

2019

50

Testing for carcinogenicity of pharmaceuticals

1997

112

Joint COM/COC on the significance of low level exposures to DNA adduct inducing chemicals

1996

48

‘Risk assessment methodologies and approaches for mutagenic and carcinogenic substances’, Preliminary Report by the EU Scientific Committees on Consumer Products, on Health and Environmental Risks, and on Emerging and Newly-Identified Risks on

2008

280

Subject:

Carcinogenicity studies

Year

Page

 

in rats, Minimum duration of

2001

121

 

in rats, Minimum duration of

2002

130

 

OECD Guidance document for the performance of chronic toxicity and

2009

225

 

Revision of OECD Test Guidelines for

2008

282

 

tobacco products, testing of

2009

219

 

Longevity of carcinogenicity studies: consideration of a database prepared by the Pesticides Safety Directorate

2000

109

Nephropathy observed in a 2-year carcinogenicity study

2008

12

T25 to estimate carcinogenic potency

1995

72

Validation of short-term carcinogenicity tests using transgenic animals, Presentation on

1999

73

Subject:

Carrageenan

Year

Page

Allergic food intolerance, COT evaluation of

1997

11

Immune system, possible effects due to uptake by the gut-associated lymphoid tissues.

1993

12

Infant formulae, COT evaluation of use in

1991

14

Subject:

Cell lines expressing human xenobiotic metabolising enzyme in mutagenicity testing

Year

Page

COM review of

1995

38

Subject:

Cell transformation assays

Year

Page

COM review of

1994

26

COM review of

2012

44

For the prediction of carcinogens

2012

37

Subject:

Chemical risk assessment

Year

Page

Evolving approaches to,

2007

23, 38

Interaction between genotype and chemicals in the environment on the induction of cancer in risk assessment

2011

53

Subject:

Childhood cancer

Year

Page

Age as an independent risk factor for chemically induced acute myelogenous leukaemia in children

2008

276

Childhood leukaemia and residence near sources of traffic exhaust and petrol fumes: review of the possible associations between

2005

143

Hazard proximities in Great Britain (from 1953 to 1980)

1997

110

Ongoing COC review of

2004

191

Ongoing COC review of

2005

134

Paternal smoking and

1997

68

Subject:

Children

Year

Page

Research project (T07040) investigating the effect of mixtures on certain food colours and a preservative on behaviour in

2007

8, 49

Children’s Environment and Health Strategy for the UK

2008

9

Subject:

Chlordecone

Year

Page

Endosulfan, pentachlorobenzene and in the infant diet

2013

18

Subject:

Chlorinated and brominated contaminants

Year

Page

in shellfish, farmed and wild fish

2006

10, 67

Subject:

Chlorinated drinking water

Year

Page

Mutagenic activity of

1991

32

Epidemiology and cancer

1992

55

and cancer

Year

Page

Chlorinated drinking water

2007

185

Chlorinated drinking water

2008

278, 285

and reproductive outcomes

Year

Page

Chlorinated Drinking Water and

1998

8

Chlorinated drinking water and

2001

18

Chlorinated drinking water

2004

8, 46

Chlorinated paraffins in food

2009

13, 111

Chlorination disinfection by-products  and risk of congenital anomalies in England and Wales –

new SAHSU study

2008

9

Subject:

Chlorine and chlorine dioxide as flour treatment agents

Year

Page

COM review of

1993

33

COT and COM review of

1996

7, 36

Subject:

Chlorobenzenes

Year

Page

COT review of

1997

12

2-Chlorobenzylidene malonitrile (CS)

Year

Page

COT review of

1998

32

new formulation of, and PAVA (Nonivamide) sprays: combined use and CS Spray

 

 

new formulation of PAVA (Nonivamide) and CS Spray respectively

2017

28

Ongoing work, co-exposure

2005

17

co-exposure

2006

7, 21

Review of CS Spray as a chemical incapacitant in relation to potential public health concerns

1999

7, 51

Combined use of CS (2-chloro-benzylidene malonitrile) and PAVA (nonivamide) (captor 2) irritant sprays

2013

14

Subject:

Chlorodibromomethane and chloroform

Year

Page

See trihalomethanes in drinking water

1994

22, 23, 32

Subject:

Chlorophenols

Year

Page

COM review of genotoxicity

2011

45

genotoxicity of

2012

37

Subject:

Cholangiocarcinoma

Year

Page

Evidence for an increase in mortality rates from intrahepatic cholangiocarcinoma in England and Wales 1968-1996

2000

107

in the rat

2005

155

Subject:

Chromium picolinate

Year

Page

COM ongoing review of

2003

141

COM review of the available information on the mutagenicity of trivalent chromium and specifically on chromium picolinate

2004

135, 148

Subject:

Chromium VI

Year

Page

COM review of

2015

36

Subject:

Chrysotile-substitutes,

Year

Page

Carcinogenic risks

1998

50

Subject:

Chymosin (enzyme)

Year

Page

from genetically modified Escherichia coli K12 in cheese manufacture

1991

16, 28

Enzyme submission to COT

2000

16

Enzyme submission; chymosin preparation derived from GM aspergillus niger var. awamori

2002

10

Subject:

Climate change

Year

Page

COC evaluation of

2011

52

Subject:

COC guidance

Year

Page

Review of

2001

142

Revision of

2002

134

COC template

2002

129

COM template

2002

87

on a strategy for the risk assessment of carcinogens

2004

188

Subject:

COM guidance

Year

Page

On ICH guidelines: Genotoxicity: A standard battery for genotoxicity testing of pharmaceuticals (S2B) and consideration of the mouse lymphoma assay

 

1997

 

75

Joint COM/COC on the significance of low level exposures to DNA adduct inducing chemicals

1996

48

Joint symposium with COM on use of target organ mutagenicity in carcinogen risk assessment

2004

192

Joint meeting of COT/COM on use of target organ mutagenicity assays in carcinogen risk assessment

2005

92, 124

Subject:

CONCAWE

Year

Page

Assessment of exposure to petrol vapour

2005

145

Assessment of exposure to benzene vapour

2005

146

Subject:

Comet Assay

Year

Page

in mutagenicity testing strategies

1998

35

published literature on the use of this assay to detect chemical mutagens

1995

39

Statement on joint COC and COM meeting 9 June 2005

2005

125

Statement on a comparison of the relative performance of the in vivo rat liver UDS assay and the in vivo Comet assay

2006

249

Subject:

Comfrey

Year

Page

Report, pyrrolizidine alkaloid (PA), in vivo data

1992

19

results of a survey of comfrey

1994

7

Subject:

Committee procedures

Year

Page

Code of Conduct for Observers

2007

18

Code of practice, revision of COT

2020

21

Code of Practice for Scientific Advisory Committees CoPSAC) second round of consultation

2001

106

Code of Practice for Scientific Advisory Committees, the updating of.

2007

18

Consultation document for updating the Code of Practice for Scientific Advisory Committees

2010

23

EFSA consultation on draft guidance on biological relevance

2017

17

EFSA consultation on draft guidance on the risk assessment of substances present in food intended for infants below 16 weeks of age

2017

19

EFSA consultation on draft guidance on weight of evidence

2017

18

EFSA opinion on statistical significance and biological relevance

2011

22

Draft EFSA protocol for a systematic review on health outcomes related to the age of introduction of complementary food for the scientific assessment of the appropriate age of introduction of complementary feeding into an infant’s diet

2017

20

EFSA consultation on draft EFSA/ECHA guidance for the identification of endocrine disruptors in the context of Regulations (EU) No 528/2012 and (EC) No 1107/2009

2018

17

EFSA consultation on draft guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain: Part 1, human and animal health

2018

18

EFSA consultation on draft guidance on threshold of toxicological concern approach

2018

20

EFSA public consultation on draft Scientific Opinion on evaluation of the health risks related to the presence of cyanogenic glycosides in foods other than raw apricot kernels

2018

20

Public consultation on the EFSA Opinion on “Risk for animal and human health related to the presence of dioxins and dioxin-like PCBs in feed and food.”

2018

20

EFSA public consultation on the MIXTOX guidance

2018

21

EFSA safety assessment of certain flavouring substances, COM consideration

2018

42

EFSA consultation on genotoxicity of mixtures

2018

42

EFSA consultation on phthalates

2019

14

EFSA consultation on the EFSA opinion on risk to public health related to the presence of ochratoxin in food.

2020

22

EFSA Public consultation on the EFSA draft Opinion “Risk to human health related to the presence of perfluoroalkyl substances in food

2020

23

EFSA consultation on the EFSA opinion on risks for animals and human health related to the presence of glycoalkaloids in feed and food, in particular in potatoes and potato-derived products

2020

24

EFSA Public consultation on the EFSA draft “Update of the risk assessment of nickel in food and drinking water”

2020

25

EFSA consultation on the EFSA opinion on the update of the risk assessment of hexabromocyclododecanes (HBCDDs) in food

2020

26

EFSA recommendations on Default values to be used in risk assessment in the absence of actual measured data

2012

7

Review of the 2018 EFSA opinion on dioxins

2021

18

Review of the 2021EFSA opinion on titanium dioxide

2021

23

Draft EFSA Scientific Committee Opinion on scientific criteria for grouping chemicals into assessment groups for human risk assessment of combined exposure to multiple chemicals

2021

26

Draft EFSA Scientific Committee Opinion on biological plausibility of non-monotonic dose responses and their impact on the risk assessment

2021

27

EFSA draft opinion on “Identification and prioritisation for risk assessments of phthalates, structurally similar substances potentially used as plasticisers in materials and articles intended to come into contact with food” and “draft protocol for the exposure assessment as part of the safety assessment of phthalates, structurally similar substances potentially used as plasticisers in materials and articles intended to come into contact with food”

2021

28

Food Standards Agency review of scientific committees

2001

24

Good Practice Agreement for Scientific Advisory Committees

2006

16

Public Consultation on Code of Practice for Scientific Advisory Committees and Councils

,2021

29

Horizon Scanning: Multiple emerging or developing topics of importance within the COT / COM / COC remit.

Every year

Consult individual report

In the light of the Phillips enquiry (COC)

2001

9, 106

Open Meetings – review of procedure

2006

17

Peer review by EU-ANSA agencies

2017

20

Performance evaluation for Committee members

2006

17

Procedure for holding COT meetings in open session

2003

18

Quinquennial Review of the COT

2011

23

Reviews of risk procedures used by Government advisory Committees dealing with food (COM)

2000

22, 110

Second round of consultation

2003

12, 106

Uncertainty framework from a social science perspective

2011

25

WHO public consultation on the JECFA/JMPR update of Chapter 5 (EHC 240)

2020

26, 51

Subject:

Committee workshops

Year

Page

Bystander Risk Assessment Working Group (BRAWG)

2011

26

Diet and drug interaction

2005

7

ECETOC workshop on use of T25 in chemical carcinogen evaluation

2001

141

Epigenetics in carcinogenesis

2016

42

Epigenetics, transgenerational

2008

19, 36

Exploring Dose- response

2020

21

Genotoxicity data, interpretation of

2020

48

ILSI/HESI workshop on less-than-lifetime exposure to carcinogens

2012

44

International workshop on the categorisation of mutagens

2001

108

PBPK for regulators

2020

22

Social Science insights for risk assessment

2006

17

Subject:

Contaminants in the diet of infants and young children

Year

Page

Overarching statement. 

2019

8

possible health risks from the exposure of infants to HBCDDs in breast milk, dust and food

2014

12

contaminants in- overarching statement. 

2019

8

Subject:

Contaminants in soil

Year

Page

assessing the possible risks to human health associated with exposure to

2001

10

Updated framework guidance, establishing a TDI

2008

9

new screening levels

2013

15, 54

Subject:

Copper

Year

Page

in the infant diet

2018

10

Subject:

Coumarin

Year

Page

And liver cancer, COT review of

1998

29, 41

Subject:

CRISPR gene editing technology-

Year

Page

potential for genotoxicity

2018

41

Subject:

CS Sabre 540010-01,

Year

Page

new formulation

2018

16

Subject:

Cyanogenic glycosides

Year

Page

in apricot kernels

2006

7, 29

EFSA public consultation on draft Scientific Opinion on evaluation of the health risks related to the presence of cyanogenic glycosides in foods other than raw apricot kernels

2018

20

Subject:

Cyclamate

Year

Page

COT review of

1995

6

Subject:

Cycloastragenol

Year

Page

COC evaluation of

2015

42