Abbreviations - Paving the way for a UK Roadmap
In this guide
In this guide|
Replacement, Reduction and Refinement |
3Rs |
|
Adsorption, Distribution, Metabolism, Excretion |
ADME |
|
Artificial Intelligence |
AI |
|
Adverse Outcome Pathway |
AOP |
|
Computational fluid dynamics |
CFD |
|
chemical-specific adjustment factor |
CSAF |
|
Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment |
COT |
|
Contract research organization |
CROs |
|
Cytochromes P450 |
CYPs |
|
developmental and reproductive toxicology |
DART |
|
Food Standards Agency |
FSA |
|
European Union |
EU |
|
Good Laboratory Practice |
GLP |
|
HTS |
High Throughput Screeninga |
|
Integrated Approaches to Testing and Assessment |
IATA |
|
Integrated chemical environment |
ICE |
|
In vitro to in vivo extrapolations |
IVIVE |
|
molecular initiating events |
MIEs |
|
Mode of Action |
MoA |
|
New Approach Methodologies |
NAMs |
|
Next generation risk assessment |
NGRA |
|
registration, evaluation, authorisation and restriction of chemicals |
REACH |
|
pharmacokinetic modelling and simulation |
PBPK |
|
Quantitative Structure Activity Relationship |
QSAR |
|
Toxicological Concern |
TTC |
|
toxicodynamics |
TD |
|
toxicokinetics |
TK |
|
Toxic Substance Control Act |
TSCA |
|
Value of a Life Year |
VOLY |
|
Weight of Evidence |
WoE |
|
Willingness-To-Pay for a Quality Adjusted Life-Year |
WTP-QALY |