References - (BPA) in foodstuffs – Reproductive and Developmental Toxicity
In this guide
In this guideAcevedo N, Rubin BS, Schaeberle CM and Soto AM, 2018. Perinatal BPA exposure and reproductive axis function in CD-1 mice. Reproductive Toxicology, 79, 39–46. https://doi.org/10.1016/j.reprotox.2018.05.002.
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Bodin J, Bølling AK, Becher R, Kuper F, Løvik M and Nygaard UC, 2014. Transmaternal bisphenol A exposure accelerates diabetes Type 1 development in NOD mice. Toxicological Sciences, 137(2), 311–323. https://doi.org/10.1093/toxsci/kft242.
Boudalia S, Berges R, Chabanet C, Folia M, Decocq L, Pasquis B, Abdennebi-Najar L and Canivenc-Lavier MC, 2014. A multi-generational study on low-dose BPA exposure in Wistar rats: Effects on maternal behavior, flavor intake and development. Neurotoxicology and Teratology, 41, 16–26. https://doi.org/10.1016/j.ntt.2013.11.002.
Brandt JZ, Silveira LTR, Grassi TF, Anselmo-Franci JA, Fávaro WJ, Felisbino SL, Barbisan LF and Scarano WR, 2014. Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats. Reproductive Toxicology, 43, 56–66. https://doi.org/10.1016/j.reprotox.2013.11.001.
Brouard V, Guénon I, Bouraima-Lelong H and Delalande C, 2016. Differential effects of bisphenol A and estradiol on rat spermatogenesis’ establishment. Reproductive Toxicology, 63, 49–61. https://doi.org/10.1016/j.reprotox.2016.05.003.
Buck Louis GM, Sundaram R, Sweeney AM, Schisterman EF, Maisog J and Kannan K, 2014. Urinary bisphenol A, phthalates, and couple fecundity: The Longitudinal Investigation of Fertility and the Environment (LIFE) Study. Fertility and Sterility, 101(5), 1359–1366. https://doi.org/10.1016/j.fertnstert.2014.01.022.
Buck Louis GM, Smarr MM, Sun LP, Chen Z, Honda M, Wang W, Karthikraj R, Weck J and Kannan K, 2018. Endocrine disrupting chemicals in seminal plasma and couple fecundity. Environmental Research, 163, 64–70. https://doi.org/10.1016/j.envres.2018.01.028.
Burstyn I, Martin JW, Beesoon S, Bamforth F, Li QZ, Yasui Y and Cherry NM, 2013. Maternal exposure to bisphenol-A and fetal growth restriction: A case-referent study. International Journal of Environmental 12706 Research and Public Health, 10(12), 7001–7014. https://doi.org/10.3390/ijerph10127001.
Camacho L, Lewis SM, Vanlandingham MM, Olson GR, Davis KJ, Patton R, Twaddle NC, Doerge DR, Churchwell MI, Bryant MS, Mclellen FM, Woodling K, Felton RP, Maisha MP, Juliar BE, Gamboa da Costa G and Delclos KB, 2019. NTP CLARITY-BPA report (2018). A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results. Food and Chemical Toxicology, 132. https://doi.org/10.1016/j.fct.2019.110728.
Cantonwine DE, Ferguson KK, Mukherjee B, McElrath TF and Meeker JD, 2015. Urinary bisphenol A levels during pregnancy and risk of preterm birth. Environmental Health Perspectives, 123(9), 895–901. https://doi.org/10.1289/ehp.1408126.
Cantonwine DE, Meeker JD, Ferguson KK, Mukherjee B, Hauser R and McElrath TF, 2016. Urinary concentrations of bisphenol A and phthalate metabolites measured during pregnancy and risk of preeclampsia. Environmental Health Perspectives, 124(10), 1651–1655. https://doi.org/10.1289/EHP188.
Cao YM, Qu XL, Ming Z, Yao YR and Zhang YZ, 2018. The correlation between exposure to BPA and the decrease of the ovarian reserve. International Journal of Clinical and Experimental Pathology, 11(7), 12753 3375–3382.
Casas M, Valvi D, Ballesteros-Gomez A, Gascon M, Fernández MF, Garcia-Esteban R, Iñiguez C, Martínez D, Murcia M, Monfort N, Luque N, Rubio S, Ventura R, Sunyer J and Vrijheid M, 2016. Exposure to bisphenol A and phthalates during pregnancy and ultrasound measures of fetal growth in the INMA- Sabadell cohort. Environmental Health Perspectives, 124(4), 521–528. https://doi.org/10.1016/j.envres.2015.07.024.
Castro B, Sánchez P, Torres JM and Ortega E, 2018. Effects of perinatal exposure to bisphenol A on the intraprostatic levels of aromatase and 5α-reductase isozymes in juvenile rats. Food and Chemical Toxicology, 115, 20–25. https://doi.org/10.1016/j.fct.2018.02.060.
Chavarro JE, Mínguez-Alarcón L, Chiu YH, Gaskins AJ, Souter I, Williams PL, Calafat AM, Hauser R and EARTH Study Team, 2016. Soy intake modifies the relation between urinary bisphenol A concentrations and pregnancy outcomes among women undergoing assisted reproduction. Journal of Clinical Endocrinology and Metabolism, 101(3), 1082–1090. https://doi.org/10.1210/jc.2015-3473.
Chin HB, Jukic AM, Wilcox AJ, Weinberg CR, Ferguson KK, Calafat AM, McConnaughey DR and Baird DD, 2019. Association of urinary concentrations of phthalate metabolites and bisphenol A with early pregnancy endpoints. Environmental Research, 168, 254–260. https://doi.org/10.1016/j.envres.2018.09.037.
Chouhan S, Yadav SK, Prakash J, Westfall S, Ghosh A, Agarwal NK and Singh SP, 2015. Increase in the expression of inducible nitric oxide synthase on exposure to bisphenol A: A possible cause for decline in steroidogenesis in male mice. Environmental Toxicology and Pharmacology, 39(1), 405–416. https://doi.org/10.1016/j.etap.2014.09.014.
Dere E, Anderson LM, Huse SM, Spade DJ, McDonnell-Clark E, Madnick SJ, Hall SJ, Camacho L, Lewis SM, Vanlandingham MM and Boekelheide K, 2018. Effects of continuous bisphenol A exposure from early gestation on 90 day old rat testes function and sperm molecular profiles: A CLARITY-BPA consortium study. Toxicology and Applied Pharmacology, 347, 1–9. https://doi.org/10.1016/j.taap.2018.03.021.
Dobrzyńska MM, Gajowik A, Radzikowska J, Tyrkiel EJ and Jankowska-Steifer EA, 2015. Male-mediated F1 effects in mice exposed to bisphenol A, either alone or in combination with X-irradiation. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 789–790, 36–45. https://doi.org/10.1016/j.mrgentox.2015.06.015
Dobrzyńska MM, Gajowik A, Jankowska-Steifer EA, Radzikowska J and Tyrkiel EJ, 2018. Reproductive and developmental F1 toxicity following exposure of pubescent F0 male mice to bisphenol A alone and in a combination with X-rays irradiation. Toxicology, 142–151. https://doi.org/10.1016/j.tox.2018.10.007.
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Ferguson KK, Meeker JD, Cantonwine DE, Chen YH, Mukherjee B and McElrath TF, 2016b. Urinary phthalate metabolite and bisphenol A associations with ultrasound and delivery indices of fetal growth. Environment International, 94, 531–537. https://doi.org/10.1016%2Fj.envint.2016.06.013.
Ferguson SA, Law CD and Kissling GE, 2014. Developmental treatment with ethinyl estradiol, but not bisphenol A, causes alterations in sexually dimorphic behaviors in male and female Sprague Dawley rats. Toxicological Sciences, 140(2), 374–392. https://doi.org/10.1093/toxsci/kfu077.
Franssen D, Gérard A, Hennuy B, Donneau AF, Bourguignon JP and Parent AS, 2016. Delayed neuroendocrine sexual maturation in female rats after a very low dose of bisphenol A through altered GABAergic neurotransmission and opposing effects of a high dose. Endocrinology, 157(5), 1740–1750. https://doi.org/10.1210/en.2015-1937.
Ganesan S and Keating AF, 2016. Bisphenol A-induced ovotoxicity involves DNA damage induction to which the ovary mounts a protective response indicated by increased expression of proteinS involved in DNA repair and xenobiotic biotransformation. Toxicological Sciences, 152(1), 169–180. https://doi.org/10.1093/toxsci/kfw076.
Gao GZ, Zhao Y, Li HX and Li W, 2018. Bisphenol A-elicited miR-146a-5p impairs murine testicular steroidogenesis through negative regulation of Mta3 signaling. Biochemical and Biophysical Research Communications, 501(2), 478–485. https://doi.org/10.1016/j.bbrc.2018.05.017.
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Gonzalez-Cadavid NF, 2019. Cellular-molecular signature and mechanism of BPA effects on penile erection – CLARITY-BPA grantee study results. https://doi.org/10.22427/NTP-DATA-018-00009-0001-000-9.
Grassi TF, da Silva GN, Bidinotto LT, Rossi BF, Quinalha MM, Kass L, Muñoz-de-Toro M and Barbisan LF, 2016. Global gene expression and morphological alterations in the mammary gland after gestational exposure to bisphenol A, genistein and indole-3-carbinol in female Sprague-Dawley offspring. Toxicology and Applied Pharmacology, 303, 101–109. https://doi.org/10.1016/j.taap.2016.05.004.
Guignard D, Gayrard V, Lacroix MZ, Puel S, Picard-Hagen N and Viguié C, 2017. Evidence for bisphenol A- induced disruption of maternal thyroid homeostasis in the pregnant ewe at low level representative of human exposure. Chemosphere, 182, 458–467. https://doi.org/10.1016/j.chemosphere.2017.05.028.
Gurmeet KSS, Rosnah I, Normadiah MK, Das S and Mustafa AM, 2014. Detrimental effects of bisphenol A on development and functions of the male reproductive system in experimental rats. Excli Journal, 13,151–160.
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Hu Y, Yuan DZ, Wu Y, Yu LL, Xu LZ, Yue LM, Liu L, Xu WM, Qiao XY, Zeng RJ, Yang ZL, Yin WY, Ma YX 13401 and Nie Y, 2018. Bisphenol A initiates excessive premature activation of primordial follicles in mouse ovaries via the PTEN signalling pathway. Reproductive Sciences, 25(4), 609–620. https://doi.org/10.1177/1933719117734700.
Huang DY, Zheng CC, Pan Q, Wu SS, Su X, Li L, Wu JH and Sun ZY, 2018. Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats. Scientific Reports, 8(1), 490. https://doi.org/10.1038/s41598-017-18869-8.
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Jukic AM, Calafat AM, McConnaughey DR, Longnecker MP, Hoppin JA, Weinberg CR, Wilcox AJ and Baird DD, 2016. Urinary concentrations of phthalate metabolites and bisphenol A and associations with follicular-phase length, luteal-phase length, fecundability, and early pregnancy loss. Environmental Health Perspectives, 124(3), 321–328. doi:10.1289/ehp.1408164. https://doi.org/10.1289/ehp.1408164.
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Kass L, Durando M, Altamirano GA, Manfroni-Ghibaudo GE, Luque EH and Muñoz-de-Toro M, 2015. Prenatal bisphenol A exposure delays the development of the male rat mammary gland. Reproductive Toxicology, 54, 37–46. https://doi.org/10.1016/j.reprotox.2014.02.001.
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Lathi RB, Liebert CA, Brookfield KF, Taylor JA, vom Saal FS, Fujimoto VY and Baker VL, 2014. Conjugated bisphenol A in maternal serum in relation to miscarriage risk. Fertility and Sterility, 102(1), 123–128. https://doi.org/10.1016/j.fertnstert.2014.03.024.
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Lee YM, Hong YC, Ha M, Kim Y, Park H, Kim HS and Ha EH, 2018. Prenatal bisphenol-A exposure affects fetal length growth by maternal glutathione transferase polymorphisms, and neonatal exposure affects child volume growth by sex: From multiregional prospective birth cohort MOCEH study. Science of the Total Environment, 612, 1433–1441. https://doi.org/10.1016/j.scitotenv.2017.08.317.
Lejonklou MH, Christiansen S, Örberg J, Shen L, Larsson S, Boberg J, Hass U and Lind PM, 2016. Low-dose developmental exposure to bisphenol A alters the femoral bone geometry in Wistar rats. Chemosphere 164, 339–346. https://doi.org/10.1016/j.chemosphere.2016.08.114.
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Leung YK, Govindarajah V, Cheong A, Veevers J, Song D, Gear R, Zhu XG, Ying J, Kendler A, Medvedovic M, Belcher S and Ho SM, 2017. Gestational high-fat diet and bisphenol A exposure heightens mammary cancer risk. Endocrine-Related Cancer 24(7), 365–378. https://doi.org/10.1530/erc-17-0006.
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Meng Y, Lin R, Wu F, Sun Q and Jia L, 2018. Decreased capacity for sperm production induced by perinatal bisphenol A exposure is associated with an increased inflammatory response in the offspring of C57BL/6 male mice. International Journal of Environmental Research and Public Health, 15(10). https://doi.org/10.3390/ijerph15102158.
Mínguez-Alarcón L, Gaskins AJ, Chiu YH, Williams PL, Ehrlich S, Chavarro JE, Petrozza JC, Ford JB, Calafat AM, Hauser R and EARTH Study Team, 2015. Urinary bisphenol A concentrations and association with in vitro fertilization outcomes among women from a fertility clinic. Human Reproduction, 30(9), 2120– 2128. https://doi.org/10.1093/humrep/dev183.
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Montévil M, Acevedo N, Schaeberle CM, Bharadwaj M, Fenton SE and Soto AM, 2020. A combined morphometric and statistical approach to assess nonmonotonicity in the developing mammary gland of rats in the CLARITY-BPA study. Environmental Health Perspectives, 128(5), 57001. https://doi.org/10.1289/ehp6301.
Moore-Ambriz TR, Acuña-Hernández DG, Ramos-Robles B, Sánchez-Gutiérrez M, Santacruz-Márquez R, Sierra-Santoyo A, Piña-Guzmán B, Shibayama M and Hernández-Ochoa I, 2015. Exposure to bisphenol A in young adult mice does not alter ovulation but does alter the fertilization ability of oocytes. Toxicology and Applied Pharmacology, 289(3), 507–514. https://doi.org/10.1016/j.taap.2015.10.010.
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Olukole SG, Ajani SO, Ola-Davies EO, Lanipekun DO, Aina OO, Oyeyemi MO and Oke BO, 2018. Melatonin ameliorates bisphenol A-induced perturbations of the prostate gland of adult Wistar rats. Biomedicine and Pharmacotherapy, 105, 73–82. https://doi.org/10.1016/j.biopha.2017.05.125.
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