Per- and polyfluoroalkyl substances: evaluation of thyroid effects using in vitro data - PFAS/2023/05

Annex C

PFAS/2023/05

Last updated: 24 September 2025

This is a paper for discussion. This does not represent the views of the Committee and should not be cited.

Table 26 PFSA chemical structures and molecular weight

CAS Number is either that given in the study, or identified based on the chemical name given in the study.

PFAS

CAS no.

Structure (source: ChemSpider)

Molecular weight (g/mol)

PFBS

375-73-5

[sulphonate 45187-15-3]

[potassium salt 29420-49-3]

ChemSpider 2D Image | EK5930000 | C4HF9O3S.

The picture is the chemical structure of PFBS, shown as a vertical image in black line and green, brown and red text.

300.10

[299.09]

[338.19]

PFHxS

355-46-4

[sulphonate 108427-53-8]

[potassium salt 3871-99-6]

The chemical structure of PFHxS.

The picture is the chemical structure of PFHxS, shown as a horizontal image in black line and green, brown and red text.

400.12

[399.11]

[438.21]

PFOS

1763-23-1

[sulphonate 45298-90-6]

[potassium salt 2795-39-3]

The chemical structure of PFOS.

The picture is the chemical structure of PFOS, shown as a vertical image in black line and green, brown and red text.

500.13

[499.12]

[538.22]

L-PFDS

 

No CAS No. found

No structure available

622.1

Weiss et al. (2009).

Table 27 PFSIA chemical structure and molecular weight

CAS Number is either that given in the study, or identified based on the chemical name given in the study.

PFAS

CAS no.

Structure (source: ChemSpider)

Molecular weight (g/mol)

L-PFOSi

 

 

No CAS No. located

No structure available

506.1

Weiss et al. (2009).

Table 28 PFCA chemical structure and molecular weight

CAS Number is either that given in the study, or identified based on the chemical name given in the study.

PFAS

CAS no.

Structure (source: ChemSpider)

Molecular weight (g/mol)

PFBA

375-22-4

The chemical structure of PFBA

The picture is the chemical structure of PFBA, shown as an angled vertical image in black line with green and red text.

214.04

PFPeA

2706-90-3

The chemical structure of PFPeA

The picture is the chemical structure of PFPeA, shown as an angled vertical image in black line with green and red text.

264.05

PFHxA

307-24-4

The chemical structure of PFHxA

The picture is the chemical structure of PFHxA, shown as an angled vertical image in black line with green and red text.

314.05

 

7H-PFHpA

1546-95-8

The chemical structure of 7H-PFHpA

The picture is the chemical structure of 7H-PFHpA, shown as an angled vertical image in black line with green and red text.

346.07

6:2 FTUA

70887-88-6

The chemical structure of 6:2 FTUA.

The picture is the chemical structure of 6:2 FTUA, shown as an horizontal image in black line with green and red text.

358.08

PFHpA

375-85-9

The chemical structure of PFHpA

The picture is the chemical structure of PFHpA, shown as an horizontal image in black line with green and red text.

364.06

PFOA

335-67-1

The chemical structure of PFOA

The picture is the chemical structure of PFOA, shown as an angled vertical image in black line with green and red text.

414.07

PFNA

375-95-1

The chemical structure of PFNA.

The picture is the chemical structure of PFNA, shown as an angled vertical image in black line with green and red text.

464.08

PFDA

335-76-2

The chemical structure of PFDA

The picture is the chemical structure of PFDA, shown as a horizontal image in black line with green and red text.

514.08

PFUnA

2058-94-8

The chemical structure of PFUnA

The picture is the chemical structure of PFUnA shown as an angled horizontal image in black line with green and red text.

564.09

PFDoA

307-55-1

 

The chemical structure of PFDoA.

The picture is the chemical structure of PFDoA shown as an angled horizontal image in black line with green and red text.

614.1

PFTrDA

72629-94-8

The chemical structure of PFTrDA.

The picture is the chemical structure PFTrDA shown as an angled horizontal image in black line with green and red text.

664.1

PFTeDA

376-06-7

The chemical structure of PFTeDA.

The picture is the chemical structure PFTeDA shown as an angled horizontal image in black line with green and red text.

714.11

Table 29 PFPA chemical structure and molecular weight

CAS Number is either that given in the study, or identified based on the chemical name given in the study.

PFAS

CAS no.

Structure (source: ChemSpider)

Molecular weight (g/mol)

C6 PFPA

 

 

356-42-3

The chemical structure of C6 PFPA.

The picture is the chemical structure C6 PFPA shown as 1 horizontal line structure and another horizontal right angled line structure in black line with green and red text.

310.05

Table 30 FTOH chemical structure and molecular weight

CAS Number is either that given in the study, or identified based on the chemical name given in the study.

PFAS

CAS no.

Structure (source: ChemSpider)

Molecular weight (g/mol)

6:2 FTOH

647-42-7

The chemical structure of 6:2 FTOH.

The picture is the chemical structure 6:2 FTOH shown as a horizontal image in black line with green and red text.

364.1

8:2 FTOH

678-39-7

The chemical structure of 8:2 FTOH.

The picture is the chemical structure 8:2 FTOH shown as a horizontal image in black line with green and red text.

464.12

10:2 FTOH

865-86-1

The chemical structure of 10:2 FTOH.

The picture is the chemical structure 10:2 FTOH shown as an angled vertical image in black line with green and red text.

564.13

Table 31 FOSE chemical structure and molecular weight

CAS Number is either that given in the study, or identified based on the chemical name given in the study.

PFAS

CAS no.

Structure (source: ChemSpider)

Molecular weight (g/mol)

N-MeFOSA

31506-32-8

N-MeFOSA

The picture is the chemical structure N-MeFOSA shown as an angled vertical image in black line with green, red and blue text.

513.17

N-EtFOSA

4151-50-2

The chemical structure of N-EtFOSA.

The picture is the chemical structure N-EtFOSA shown as a horizontal image in black line with green, red, blue and brown text.

527.2

N-MeFOSE

24448-09-7

The chemical structure of N-MeFOSE.

The picture is the chemical structure N-MeFOSE shown as an angled horizontal image in black line with green, red, blue and brown text.

557.23

N-EtFOSE

1691-99-2

The chemical structure of N-EtFOSE.

The picture is the chemical structure of N-EtFOSE shown as an angled horizontal image in black line with green, red, blue and brown text.

571.25

Table 32 FOSA chemical structure and molecular weight

CAS Number is either that given in the study, or identified based on the chemical name given in the study.

PFAS

CAS no.

Structure (source: ChemSpider)

Molecular weight (g/mol)

PFOSA

754-91-6

The chemical structure of PFOSA.

The picture is the chemical structure of PFOSA shown as a horizontal image in black line with green, red, blue and brown text.

499.15

N,N-Me2FOSA

213181-78-3

 

 

The chemical structure of N,N-Me2FOSA.

The picture is the chemical structure of N,N-Me2FOSA shown as an angled horizontal image in grey line with pink, red, blue and yellow text.

 

527.2

Table 33 New generation substitutes chemical structure and molecular weight

CAS Number is either that given in the study, or identified based on the chemical name given in the study.

PFAS

CAS no.

Structure (source: ChemSpider)

Molecular weight (g/mol)

C6O4

1190931-41-9

The chemical structure of C6O4.

The picture is the chemical structure of C6O4 shown as an horizontal image in black line with red and green text.

340.05

F-53B

73606-19-6

The chemical structure of F-53B.

The picture is the chemical structure of F-53B shown in 2 parts approximately 110 degrees angled towards each other. These structures are shown in black line with red, green, brow and purple text.

570.67