List of Abbreviations
In this guide
In this guideThis is a paper for discussion. This does not represent the views of the Committee and should not be cited.
6:2 FTOH |
6:2 Fluorotelomer alcohol |
6:2 FTUA |
2H-Perfluoro-2-octenoic acid (6:2) |
7H PFHpA |
7H-Perfluoroheptanoic acid |
8:2 FTOH |
8:2 Fluorotelomer alcohol |
10:2 FTOH |
10:2 Fluorotelomer alcohol |
AhR |
Aryl hydrocarbon receptor |
AhR-REP |
AhR-mediated relative potency |
AhR-tact |
AhR transactivity |
C6O4 |
Perfluoro{acetic acid, 2-[(5-methoxy-1,3-dioxolan-4-yl) oxy]}, ammonium salt |
C6 PFPA |
Pentafluoropropionic anhydride |
cAMP |
Cyclic adenosine monophosphate |
CAS |
Chemical abstract service |
COT |
Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment |
DMSO |
Dimethyl sulfoxide |
EFSA |
European Food Safety Authority |
EtOH |
Ethyl alcohol |
EU |
European Union |
F-53B |
6:2 chlorinated polyfluorinated ether sulfonate |
FOSA |
Perfluorinated sulfonamide |
FOSE |
N-alkylperfluorooctane sulfonamidoethanols |
FRTL |
Fischer rat thyroid cell line |
F-T4 |
Fluorescein-thyroxine |
FTOH |
Fluorotelomer alcohol |
GL |
Guideline |
GLP |
Good laboratory practice |
HBGV |
Health-based guidance value |
HEK |
Human Embryonic Kidney |
IC50 |
Inhibitory concentration 50% |
LDH |
Lactate dehydrogenase |
LOEC |
Lowest observed effect concentration |
L-PFDS |
Perfluorodecane sulfonate |
L-PFOSi |
Perfluorooctane sulfinate |
MC540 |
Merocyanine 540 |
MOEC |
Maximum observed effect concentration |
NA |
Not applicable |
ND |
Not detected |
N-EtFOSA |
2-(N-ethylperfluoro-1-octane sulfonamido) ethanol |
N-EtFOSE |
2-(N-ethylperfluoro-1-octane sulfonamido) ethanol |
NHT |
Normal Human Thyroid |
NIS |
Sodium/iodide symporter |
N-MeFOSA |
N-methyl perfluorooctane sulfonamide |
N-MeFOSE |
2-(N-methylperfluoro-1-octane sulfonamido) ethanol |
N,N-Me2FOSA |
N,N-dimethyl perfluorooctane sulfonamide |
PFAS |
Per- and polyfluoroalkyl substances |
PFBA |
Perfluorobutanoate / Perfluorobutanoic acid |
PFBS |
Perfluorobutane sulfonate / Perfluorobutane sulfonic acid |
PFCs |
Poly- and perfluorinated compounds |
PFCA |
Perfluoroalkyl carboxylic acids |
PFDA |
Perfluorodecanoate / Perfluorodecanoic acid |
PFDoA |
Perfluorododecanoic acid |
PFHpA |
Perfluoroheptanoate / Perfluoroheptanoic acid |
PFHxA |
Perfluorohexanoate / Perfluorohexanoic acid |
PFHxDA |
Perfluorohexadecanoic acid |
PFHxS |
Perfluorohexane sulfonate |
PFNA |
Perfluorononanoate / Perfluorononanoic acid |
PFOA |
Perfluorooctanoate / Perfluorooctanoic acid |
PFOS |
Perfluorooctane sulfonate / Perfluorooctane sulfonic acid |
PFOSA |
Perfluorooctane sulfonamide |
PFOSi |
Perfluorooctane sulfinic acid |
PFPA |
Perfluoroalkyl phosphonic acids |
PFPeA |
Perfluoropentanoate / Perfluoropentanoic acid |
PFSA |
Perfluorosulfonic acids |
PFSIA |
Perfluoroalkane sulfinic acid |
PFTrDA |
Perfluorotridecanoate /Perfluorotridecanoic acid |
PFTeDA |
Perfluorotetradecanoate / Perfluorotetradecanoic acid |
PFUnA |
Perfluoroundecanoate / Perfluoroundecanoic acid |
PPAR |
Proliferator-activated receptor |
RNA |
Ribonucleic acid |
ROS |
Reactive oxygen species |
RP |
Relative potency |
T3 |
Triiodothyronine |
T4 |
Thyroxine |
TBG |
Thyroxine-binding globulin |
TCDD |
2,3,7,8 -Tetrachlorodibenzo-p-dioxin |
TH |
Thyroid hormone |
TPO |
Thyroperoxidase |
TR |
Thyroid hormone receptor |
TSH |
Thyroid stimulating hormone |
TSH-R |
Thyroid stimulating hormone receptor |
TTR |
Transthyretin (thyroid hormone transport protein) |
US EPA |
United States Environmental Protection Agency |
WT |
Wild type |