OECD guidelines - COM 2022

2.33       Members were informed of a proposal from Norway to update OECD Test Guideline 489 on the in vivo alkaline comet assay to include the investigation of germ cells. Currently any modifications have not been sufficiently validated, but it was early stages for the OECD.

2.34       The COM also heard that the OECD Test Guideline 488 Transgenic rodent somatic and gene mutation assays had been updated and published.