Statement on the potential risk to human health of turmeric and curcumin supplements

List of Abbreviations and Technical Terms

COT/2024/07

Last updated: 09 December 2024

ADI

Acceptable Daily Intake

AFSCA

ALP

Belgium’s Federal Agency for Food Chain Safety

Alkaline Phosphatase

ALT

Alanine Aminotransferase

ANS Panel

Scientific Panel on Food Additives and Nutrient Sources Added to Food

ANSES

French Agency for Food, Environmental and Occupational Health & Safety

AST

Aspartate Aminotransferase

AUC

Area Under the Curve

As

Arsenic

BDMC

Bisdemethoxycurcumin

BfR

German Federal Institute for Risk Assessment

BMDL

CCM

Benchmark Dose Lower Confidence Level

Curcumin

Cd

Cadmium

CO2

Carbon Dioxide

CONTAM Panel

Scientific Panel on Contaminants in the Food Chain

COT

Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment

Cr

Chromium

DILIN

United States Drug-Induced Liver Injury Network

DMC

Desmethoxycurcumin

EC

European Commission

EFSA

European Food Safety Authority

EU

European Union

EXPOCHI

Exposure Assessments For Children In Europe

FAO

Food and Agricultural Organisations of the United Nations

GD

Gestation Day

GGT

Gamma-Glutamyl Transferase

HBGVs

Health-Based Guidance Values

Hg

Mercury

HPLC

High Performance Liquid Chromatography

IARC

International Agency for Research on Cancer

IDH

Idiosyncratic Drug Hepatotoxicity

JECFA

Joint FAO-WHO Expert Committee on Food Additives

mg

Milligrams

mg/kg bw/day

Milligrams per Kilogram Bodyweight per Day

ML

Maximum Level

MOE

Margin of Exposure

MPL

Maximum Permitted Levels

mRNA

Messenger Ribonucleic Acid

NDA Panel

Scientific Panel on Nutrition, Novel Foods and Food Allergens

NDS

National Diet and Nutrition Survey

NOAEL

NTP

No-Observed-Adverse-Effect Level 

National Toxicology Program

Pb

PK

Lead

Pharmacokinetic

SBP

Systolic Blood Pressure

SCF

Scientific Committee for Food

SD

Standard Deviation

TDI

Tolerable Daily Intake

TK

Toxicokinetic

UK

United Kingdom

WHO

World Health Organisation