Annex A - Abbreviations

ADI

Acceptable daily intake

ALP

Alkaline phosphatase

ALT

Alanine aminotransferase

AMMC

3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4- methylcoumarin

API

Adiposity percentage

AST

Aspartate transaminase

BFC

7-benzyloxy-4-(trifluoromethyl)- coumarin

BMI

Body mass index

BQ

7-benzyloxyquinoline

bw

Body weight

CEC

3-cyano-7- ethoxycoumarin

CI

Confidence interval

CYP

Cytochrome P450

DES

Diethylbestrol

DMSO

Dimethylsulfoxide

EC50

Half-maximal effective concentration

EFC

7-ethoxy-4-trifloromethyl-coumarin

EMA

European Medicines Agency

ERES

Ethoxyresorufin

FSA

Food Standards Agency

GDM

Gestational diabetes mellitus

HBGV

Health-based guidance value

HPLC

High-performance liquid chromatography

IC50

Half-maximal inhibitory concentration

LCMS/MS

Liquid chromatography mass spectrometry/mass spectrometry

LOQ

Limit of quantification

MFC

7-methoxy-4-(trifuoromethyl)-coumarin

MHRA

Medicines and Healthcare products Regulatory Agency

MRES

Methoxyresorufin

MRL

Maximum residue limit

NDNS

National Diet and Nutrition Survey

NOAEL

No-observed-adverse-effect level

NP

Non-pregnant

RLE

Raspberry leaf extract

RLE-H

High-temperature, high-pressure raspberry leaf extract

RLP

Raspberry leaf powder

SACN

Scientific Advisory Committee on Nutrition

TG2

Transglutaminase 2

TDI

Tolerable daily intake

TUL

Tolerable upper intake level

UKTIS

UK Teratology Information Service

WHO

World Health Organization