EFSA public consultation on the risk for animal and human health related to the presence of dioxins and dioxin-like PCBs in feed and food

Abbreviations

TOX/2025/48

Last updated: 08 December 2025

ADME

Absorption, distribution, metabolism, excretion

AhR

Aryl hydrocarbon receptor

AOP

Adverse outcome pathway

BMD

Benchmark dose

BMDL

BMD lower credible limit

BMR

Benchmark response

CADM model

Concentration- and age-dependent model

GD

Gestation day

HBGV

Health based guidance value

LOAEL

Lowest observed adverse effect level

MoA

Mode of action

NOAEL

No observed adverse effect level

PND

Postnatal day

RP

Reference point

TEFs

Toxic equivalency factors

TEQ

Toxic equivalents

TWI

Tolerable weekly intake

UF

Uncertainty factors

COT

Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment

EFSA                  

European Food Safety Authority

EC

European Commission

FSA

Food Standards Agency

JECFA

Joint FAO/WHO Expert Committee on Food Additives

SCF

Scientific Committee for Food

SETE

Joint COT and COC Synthesis and Integration of Epidemiological and Toxicological Evidence subgroup

UNEP

United Nations Environment Programme

WHO

World Health Organisation