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Statements

COT statements and position papers

COT statements are the main form in which the Committee presents its advice. Position papers are short overviews produced more quickly than full statements. Please note that links to the national archive may not be compatible with accessibility readers

Last updated: 02 October 2020

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A

Acid sweets

Adverse reactions to acid sweets (2004)

External link to the national archive for the 2004 COT statement on adverse reactions to acid sweets

Acrylamide

Potential risks from acrylamide in the diet of infants and young children (2016)

External link to the national archive for the 2016 COT Statement on Acrylamide

Additives

Potassium-based replacements for sodium chloride and sodium-based additives (2017)

External link to the national archive for the 2017 COT statement on potassium-based replacements for sodium chloride and sodium-based additives

Health effects of mixtures of food additives (T01040/41) (2008)

External link to the national archive for the 2008 COT statement on FSA funded research on health effects of mixtures of food additives (T01040/41)

Research project (TO7040) investigating the mixtures of certain food colours and a preservative on behaviour in children (2007)

External link to the national archive for the 2007 COT statement on research project (TO7040) investigating the mixtures of certain food colours and a preservative on behaviour in children

Food additives and developmental neurotoxicity (2006)

External link to the national archive for the 2006 COT statement on food additives and developmental neurotoxicity

Research project investigating the effect of food additives on behaviour (2002)

External link to the national archive for the 2002 COT statement on a research project investigating the effect of food additives on behaviour

Alcohol

The interaction of caffeine and alcohol and their combined effects on health and behaviour (2012)

External link to the national archive for the 2012 COT Statement on the interaction of caffeine and alcohol and their combined effects on health and behaviour

Allergic disease

Maternal and infant dietary exposures and allergy, and risk of development of atopic outcomes and autoimmune disease (2017)

External link to the national archive for the 2017 COT statement on maternal and infant dietary exposures and allergy

Risks of chemical toxicity and allergic disease in relation to infant diet (2012)

External link to the national archive for the 2012 COT overarching statement on risks of chemical toxicity and allergic disease in relation to infant diet

Allergenic foods

The timing of introduction of allergenic foods (2016)

External link to the national archive for the 2016 COT statement on the timing of introduction of allergenic foods

COT joint statement on the timing of introduction of gluten into the infant diet (2011)

External link to the national archive for the 2011 joint COT statement on the timing of the introduction of gluten into the infant diet

Review of the 1998 COT recommendations on peanut avoidance (2008)

External link to the national archive for the 1998 COT statement on the review of the 1998 COT recommendations on peanut avoidance

Aluminium

Addendum to the 2013 COT statement on Aluminium (2016)

External link to the national archive for the 2016 Addendum to the 2013 COT statement on Aluminium

Potential risks from aluminium in the infant diet (2013)

External link to the national archive for the 2013 COT statement on Aluminium

Amnesic shellfish poisoning

Amnesic shellfish poisoning (ASP) (2001)

External link to the national archive for the 2001 COT statement on ASP

Arsenic

Statement on Arsenic in infants and young children (2016)

External link to the national archive for the 2016 COT statement on Arsenic

Arsenic in food: results of the 1999 total diet study (2003)

External link to the national archive for the 2003 COT statement on arsenic in food: results of the 1999 (TDS)

Aspartame

Current status of the randomized double-blind volunteer study on aspartame (2013)

External link to the national archive for 2013 COT position paper on aspartame

 

 

B

Bisphenols

Study of bisphenols in canned foods (2001)

External link to the national archive for the 2001 COT statement on a study of bisphenols in canned foods

Bisphenol A (1997)

External link to the national archive for the 1997 COT statement on bisphenol A

Bisphenol A diglycidyl ether (BADGE) in canned foods (1997)

External link to the national archive for the 1997 COT statement on BADGE in canned foods

Bitter apricot kernels

Cyanogenic glycosides in bitter apricot kernels (2006)

External link to the national archive for the 2006 COT statement on cyanogenic glycosides in bitter apricot kernels

Bracken

Risk to consumers of eating foods derived from animals that have eaten bracken (2008)

External link to the national archive for the 2008 COT statement on the risk to consumers of eating foods derived from animals that have eaten bracken

Breast implants

Further toxicity studies in the rat of a hydrogel filler for breast implants (2006)

External link to the national archive for the 2006 COT statement on further toxicity studies in the rat of a hydrogel filler for breast implants

Further toxicity study in the rat of a hydrogel filler for breast implants (2002)

External link to the national archive for the 2002 COT statement on a further toxicity study in the rat of a hydrogel filler for breast implants

Toxicity study in the rat of a hydrogel filler for breast implants (2000)

External link to the national archive for the 2000 COT statement on a toxicity study in the rat of a hydrogel filler for breast implants

Breast milk

Toxicological evaluation of chemical analyses carried out as part of a pilot study for a breast milk archive (2004)

External link to the national archive for the 2004 COT statement on a toxicological evaluation of chemical analyses carried out as part of a pilot study for a breast milk archive

Health hazards of polychlorinated biphenyls (1997)

External link to the national archive for the 1997 COT statement on the health hazards of polychlorinated biphenyls

Bromine

Organic chlorinated and brominated contaminants in shellfish, farmed and wild fish (2006)

External link to the national archive for the 2006 COT statement on organic chlorinated and brominated contaminants in shellfish, farmed and wild fish

Brominated flame retardants in fish from the Skerne-Tees rivers system (2004)

External link to the national archive for the 2004 COT statement on brominated flame retardants in fish from the Skerne-Tees rivers system

Tetrabromobisphenol A - review of toxicological data (2004)

External link to the national archive for the 2004 COT statement on tetrabromobisphenol A - review of toxicological data

The 1997 Total Diet Study - Fluorine, Bromine, and Iodine (2000)

External link to the national archive for the 2000 COT statement on the 1997 Total Diet Study - Fluorine, Bromine, and Iodine

 

 

C

Cabin air environment

Review of possible adverse health effects in the crew of commercial aircraft (2013)

External link to the national archive for the 2013 COT position paper the review of possible adverse health effects in the crew of commercial aircraft

Review of the cabin air environment, ill-health in aircraft crews and the possible relationship to smoke/fume events in aircraft (2007)

External link to the national archive for the 2007 COT statement on the review of the cabin air environment, ill-health in aircraft crews and the possible relationship to smoke/fume events in aircraft

Cadmium

The potential risks from cadmium in the infant diet (2018)

External link to the national archive for the 2018 COT statement on the potential risks from cadmium

Caffeine

The interaction of caffeine and alcohol and their combined effects on health and behaviour (2012)

External link to the national archive for the 2012 COT Statement on the interaction of caffeine and alcohol and their combined effects on health and behaviour

Reproductive effects of caffeine (2008)

External link to the national archive for the 2008 COT statement on the reproductive effects of caffeine

Reproductive effects of caffeine (2001)

External link to the national archive for the 2001 COT statement on the reproductive effects of caffeine

Cannabidiol (CBD)

Position paper on the potential risk of CBD in CBD food products (2020)

COT position paper on the potential risk of cannabidiol (CBD) in CBD food products

Chlorine

Polychlorinated naphthalenes in food (2009)

External link to the national archive for the 2009 COT statement on polychlorinated naphthalenes in food

Chlorinated paraffins in food (2009)

External link to the national archive for the 2009 COT statement on chlorinated paraffins in food

Chlorination disinfection by-products and risk of congenital anomalies in England and Wales (2008)

External link to the national archive for the 2008 COT statement on a SAHSU study on chlorination disinfection by-products and risk of congenital anomalies in England and Wales

Organic chlorinated and brominated contaminants in shellfish, farmed and wild fish (2006)

External link to the national archive for the 2006 COT statement on organic chlorinated and brominated contaminants in shellfish, farmed and wild fish

Chlorinated water and reproductive outcomes (2004)

External link to the national archive for the 2004 COT statement on chlorinated water and reproductive outcomes

Copper

Potential risks from copper in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on copper

CS

New formulation of CS - Sabre 540010-01 (2018)

External link to the national archive for the 2018 COT statement on the new formulation of CS - Sabre 540010-01

 

 

D

Dental amalgam

Toxicity of dental amalgam (1997)

External link to the national archive for the 1997 COT statement on the toxicity of dental amalgam

Developmental neurotoxicity

Food additives and developmental neurotoxicity (2006)

External link to the national archive for the 2006 COT statement on food additives and developmental neurotoxicity

Diet-drug interactions

COT/CSM one day meeting on diet-drug interactions (2006)

External link to the national archive for  the 2006 COT statement on joint COT/CSM one day meeting on diet-drug interactions

Diethyl-m-toluamide (DEET)

Review of toxicology literature on the use of topical insect repellent diethyl-m-toluamide (DEET) (2006)

External link to the national archive for  the 2006 COT update to statement on the review of toxicology literature on the use of topical insect repellent diethyl-m-toluamide (DEET)

Review of toxicology literature on the use of topical insect repellent diethyl-m-toluamide (DEET) (2002)

External link to the national archive for the 2002 COT statement on the review of toxicology literature on the use of topical insect repellent diethyl-m-toluamide (DEET)

Dioxins

Occurrence of mixed halogenated dioxins and biphenyls in UK food (2010)

External link to the national archive for the 2010 COT statement on occurrence of mixed halogenated dioxins and biphenyls in UK food

FSA funded study investigating the developmental effects of dioxin (TCDD) in rats (2007)

External link to the national archive for  the 2007 COT statement on FSA funded study investigating the developmental effects of dioxin (TCDD) in rats

2005 WHO equivalency factors for dioxins and dioxin-like compounds (2006)

External link to the national archive for  the 2006 COT statement on 2005 WHO equivalency factors for dioxins and dioxin-like compounds

Tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls (2001)

External link to the national archive for  the 2001 COT statement on the tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls

Dietary exposure to dioxins and dioxin-like PCBs (2000)

External link to the national archive for the 2000 COT statement on dietary exposure to dioxins and dioxin-like PCBs

Dioxins and dioxin-like PCBs in free-range eggs (2000)

External link to the national archive for the 2000 COT statement on dioxins and dioxin-like PCBs in free-range eggs

Disinfectants

Chlorination disinfection by-products and risk of congenital anomalies in England and Wales (2008)

External link to the national archive for the 2008 COT statement on a SAHSU study on chlorination disinfection by-products and risk of congenital anomalies in England and Wales

Commercial survey investigating the occurrence of disinfectants and disinfection by-products in prepared salads (2006)

External link to the national archive for the 2006 COT statement on a commercial survey investigating the occurrence of disinfectants and disinfection by-products in prepared salads

 

 

E

Eggs

Dioxins and dioxin-like PCBs in free-range eggs (2000)

External link to the national archive for the 2000 COT statement on dioxins and dioxin-like PCBs in free-range eggs

Elements

Results of a multi-element survey of fungi and blackberries (2000)

External link to the national archive for the 2000 COT statement on the results of a multi-element survey of fungi and blackberries

Results of multi-element surveys (1998)

COT statement on the results of multi-element surveys

External link to the national archive for the 1998 COT statement on the results of multi-element surveys

Endosulfan isomers, pentachlorobenzene and chlordecone

Endosulfan isomers, pentachlorobenzene and chlordecone (2014)

External link to the national archive for the 2014 COT statement on endosulfan isomers, pentachlorobenzene and chlordecone

E(N)NDS – e-cigarettes

Statement on the potential toxicological risks from electronic nicotine (and non-nicotine) delivery systems (E(N)NDS – e-cigarettes) (2020)
Lay summary of statement on the potential toxicological risks from electronic nicotine (and non-nicotine) delivery systems (E(N)NDS – e-cigarettes) (2020)
Framework for risk assessment of flavouring compounds in E(N)NDS – e-cigarettes (2020)

COT framework for risk assessment of flavouring compounds in electronic nicotine (and non-nicotine) delivery systems (E(N)NDS – e-cigarettes)

Energy drinks

The potential risks from “energy drinks” in the diet of children and adolescents (2019)

COT statement on Energy drinks

Lay summary on the potential risks from “energy drinks” in the diet of children and adolescents (2019)

Lay summary COT statement on Energy drinks

Interim position paper on potential risks from “energy drinks” in the diet of children and adolescents (2018)

External link to the national archive for the 2018 COT interim position paper on energy drinks

Epigenetics

Statement from a joint Committee workshop on the use of epigenetics in chemical risk assessment (2019)
Workshop on transgenerational epigenetics (2008)

External link to the national archive for the 2008 COT statement on the COT workshop on transgenerational epigenetics

 

 

F

Fish and shellfish

Organic chlorinated and brominated contaminants in shellfish, farmed and wild fish (2006)

External link to the national archive for the 2006 COT statement on organic chlorinated and brominated contaminants in shellfish, farmed and wild fish

Brominated flame retardants in fish from the Skerne-Tees rivers system (2004)

External link to the national archive for the 2004 COT statement on brominated flame retardants in fish from the Skerne-Tees rivers system

Survey of mercury in fish and shellfish update (2004)

External link to the national archive for the 2004 updated COT statement on a survey of mercury in fish and shellfish

Survey of mercury in fish and shellfish (2003)

External link to the national archive for the 2003 COT statement on a survey of mercury in fish and shellfish

Amnesic shellfish poisoning (2001)

External link to the national archive for the 2001 COT statement on ASP

Results of a survey for PCDDs, PCDFs and PCBs in Marine Fish and Fish Products (1999)

External link to the national archive for the 1999 COT statement on the results of a survey for PCDDs, PCDFs and PCBs in Marine Fish and Fish Products

Surveillance for malachite green and leucomalachite green in farmed fish (1999)

External link to the national archive for the 1999 COT statement on surveillance for malachite green and leucomalachite green in farmed fish

Fluorine

Fluorine in the 1997 Total Diet Study (2003)

External link to the national archive for  the 2003 COT statement on fluorine in the 1997 Total Diet Study

The 1997 Total Diet Study - Fluorine, Bromine, and Iodine (2000)

External link to the national archive for the 2000 COT statement on the 1997 Total Diet Study - Fluorine, Bromine, and Iodine

Folic acid

Folic Acid – Statement on the Tolerable Upper Level (TUL) (2019)

COT statement on Folic Acid

Lay summary Folic Acid – Statement on the Tolerable Upper Level (TUL) (2019)

Lay summary COT statement on Folic Acid

Position paper on the current upper level for folic acid intake (2018)

External link to the national archive for the 2018 COT position paper on the current upper level for folic acid intake

 

 

H

Halogenated contaminants

Occurrence of mixed halogenated dioxins and biphenyls in UK food (2010)

External link to the national archive for the 2010 COT statement on occurrence of mixed halogenated dioxins and biphenyls in UK food

Organic chlorinated and brominated contaminants in shellfish, farmed and wild fish (2006)

External link to the national archive for the 2006 COT statement on organic chlorinated and brominated contaminants in shellfish, farmed and wild fish

Hepatotoxicity

Glucosamine and hepatotoxicity (2009)

External link to the national archive for the 2009 COT statement on glucosamine and hepatotoxicity

Hexabromocyclododecanes (HBCDDs)

Addendum to the 2015 COT Statement on hexabromocyclododecanes (HBCDDs) (2016)

External link to the national archive for the 2016 Addendum to the 2015 COT statement on HBCDDs

Hexabromocyclododecanes (HBCDDs) (2015)

External link to the national archive for the 2015 COT statement on (HBCDDs)

Hexachlorobutadiene

Hexachlorobutadiene (2000)

External link to the national archive for the 2000 COT statement on Hexachlorobutadiene

Hexachlorocyclohexanes

Hexachlorocyclohexanes (HCHs) (2014)

External link to the national archive for the 2014 COT statement on HCHs

Hydrolysed formula

Hydrolysed cows' milk formulae (2016)

External link to the national archive for the 2016 COT statement on hydrolysed cows' milk formulae

 

 

I

Idiopathic Environmental Intolerance (IEI)

Idiopathic Environmental Intolerance (IEI) (2011)

External link to the national archive for the 2011 COT statement on IEI

Infant food and formulae

Addendum to the Overarching Statement on the potential risks from contaminants diet of infants and young children (2020)

Addendum to the COT overarching Statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

Lay summary addendum to the Overarching Statement on the potential risks from contaminants diet of infants and young children (2020)

Lay summary addendum to the COT overarching Statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

Overarching statement on the potential risks from contaminants in the diet of infants and young children (2019)

COT overarching statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

Lay summary overarching statement on the potential risks from contaminants in the diet of infants and young children (2019)

Lay summary COT overarching statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

The health effects of manganese in the diets of infants and young children (2018)

External link to the national archive for the 2018 COT statement on the health effects of manganese in the diets of infants aged 0-12 months and children aged 1-5 years

The results of the 2014 survey of metals and other elements in infant foods (2018)

External link to the national archive for the 2018 COT statement on the results of the 2014 survey of metals and other elements in infant foods

Potential risks from nickel in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on potential risks from nickel in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

The potential risks from ochratoxin A (OTA) in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on potential risks from ochratoxin A (OTA) in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

T-2 toxin (T2), HT-2 toxin (HT2) and neosolaniol (NEO) in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement of T-2 toxin (T2), HT-2 toxin (HT2) and neosolaniol (NEO) in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

The potential risks from cadmium in the infant diet (2018)

External link to the national archive for the 2018 COT statement on the potential risks from cadmium

Potential risks from methylmercury in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on methylmercury

The potential risks from excess iodine (2017)

External link to the national archive for the 2017 COT statement on the potential risks from exceed iodine

Addendum to the 2015 COT statement on potential risks from PBDEs in the infant diet (2017)

External link to the national archive for the 2017 addendum to the 2015 COT statement on potential risks from polybrominated diphenyl ethers (PBDEs) in the infant diet

Maternal and infant dietary exposures and allergy, and risk of development of atopic outcomes and autoimmune disease (2017)

External link to the national archive for the 2017 COT statement on maternal and infant dietary exposures and allergy

Hydrolysed cows' milk formulae (2016)

External link to the national archive for the 2016 COT statement on hydrolysed cows' milk formulae

The timing of introduction of allergenic foods (2016)

External link to the national archive for the 2016 COT statement on the timing of introduction of allergenic foods

Statement on Arsenic in infants and young children (2016)

External link to the national archive for the 2016 COT statement on Arsenic

Potential risks from acrylamide in the diet of infants and young children (2016)

External link to the national archive for the 2016 COT Statement on Acrylamide

Addendum to the 2013 COT statement on lead (2016)

External link to the national archive for the 2016 Addendum to the 2013 COT statement on lead

Addendum to the 2013 COT statement on Aluminium (2016)

External link to the national archive for the 2016 Addendum to the 2013 COT statement on Aluminium

Polybrominated biphenyls (PBBs) in the infant diet (2015)

External link to the national archive for the 2015 COT statement on PBBs in the infant diet

Polybrominated diphenyl ethers (PBDEs) (2015)

External link to the national archive for the 2015 COT statement on PBDEs

Hexabromocyclododecanes (HBCDDs) (2015)

External link to the national archive for the 2016 Addendum to the 2015 COT statement on (HBCDDs)

Risks from Perfluorooctane (PFOS) in the infant diet 2014

External link to the national archive for the 2014 COT statement on PFOS

Endosulfan isomers, pentachlorobenzene and chlordecone (2014)

External link to the national archive for the 2014 COT statement on endosulfan isomers, pentachlorobenzene and chlordecone

Hexachlorocyclohexanes (HCHs) (2014)

External link to the national archive for the 2014 COT statement on HCHs

Phytoestrogens (2013)

External link to the national archive for the 2013 COT statement on phytoestrogens

High levels of vitamin A in the infant diet (2013)

External link to the national archive for the 2013 COT statement on vitamin A in the infant diet

Potential risks from lead in the infant diet (2013)

External link to the national archive for the 2013 COT statement on lead

Potential risks from aluminium in the infant diet (2013)

External link to the national archive for the 2013 COT statement on aluminium in the infant diet

Risks of chemical toxicity and allergic disease in relation to infant diet (2012)

External link to the national archive for the 2012 COT overarching statement on risks of chemical toxicity and allergic disease in relation to infant diet

COT joint statement on the timing of introduction of gluten into the infant diet (2011)

External link to the national archive for the 2011 joint COT statement on the timing of the introduction of gluten into the infant diet

Uranium levels in water used to reconstitute infant formula (2006)

External link to the national archive for the 2006 COT statement on uranium levels in water used to reconstitute infant formula

Metals in infant food (2003)

External link to the national archive for the 2003 COT statement on metals in infant food

Phthalates in infant formulae (1996)

External link to the national archive for the 1996 COT statement on phthalates in infant formulae

Iodine

The potential risks from excess iodine (2017)

External link to the national archive for the 2017 COT statement on the potential risks from excess iodine

The 1997 Total Diet Study - Fluorine, Bromine, and Iodine (2000)

External link to the national archive for the 2000 COT statement on the 1997 Total Diet Study - Fluorine, Bromine, and Iodine

Iodine in cows' milk (2000)

External link to the national archive for the 2000 COT statement on iodine in cows' milk

Iodine in cows'  milk (1997)

External link to the national archive for the 1997 COT statement on iodine in cows' milk

Irritant sprays

Guidance on information required by COT for consideration of irritant sprays and their formulation (2018)

External link to the national archives for 2018 guidance on information required by COT for consideration of irritant sprays and their formulation

 

 

J

No statements yet

 

 

K

No statements yet

 

 

L

Landfill sites

COT second statement on landfill sites (2010)

External link to the national archive for the 2010 COT second statement on landfill sites

Study by the small Area Health Statistics Unit (SAHSU) on health outcomes in population living around landfill sites (2001)

External link to the national archive for the 2001 COT statement on a study by the Small Area Health Statistics Unit (SAHSU) on health outcomes in populations living around landfill sites

Also see the COT landfill statement

Lay summaries

Lay summary of the statement on interactions between xenobiotics and the human microbiota and their potential toxicological implications (2020)
Lay summary of statement on the potential toxicological risks from electronic nicotine (and non-nicotine) delivery systems (E(N)NDS – e-cigarettes) (2020)
Lay summary addendum to the Overarching Statement on the potential risks from contaminants diet of infants and young children (2020)

Lay summary addendum to the COT overarching Statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

Lay summary overarching statement on the potential risks from contaminants in the diet of infants and young children (2019)

Lay summary COT overarching statement on the potential risks from contaminants in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

Lay summary Folic Acid – Statement on the Tolerable Upper Level (TUL) (2019)

Lay summary COT statement on Folic Acid

Lay summary on the potential risks from “energy drinks” in the diet of children and adolescents (2019)

Lay summary COT statement on Energy drinks

The potential risks from cadmium in the infant diet (2018)

External link to the national archive for the 2018 COT statement on the potential risks from cadmium

Potential risks from copper in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on copper

The health effects of manganese in the diets of infants and young children (2018)

External link to the national archive for the 2018 COT statement on the health effects of manganese in the diets of infants aged 0-12 months and children aged 1-5 years

The results of the 2014 survey of metals and other elements in infant foods (2018)

External link to the national archive for the 2018 COT statement on the results of the 2014 survey of metals and other elements in infant foods

Potential risks from nickel in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on potential risks from nickel in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

The potential risks from ochratoxin A (OTA) in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on potential risks from ochratoxin A (OTA) in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

Potential risks from methylmercury in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on methylmercury

Heat not burn tobacco products (2017)

External link to the national archive for the 2017 COT statement on heat not burn tobacco products

Addendum to the 2013 COT statement on potential risks from vitamin A (2017)

External link to the national archive for the 2017 Addendum to the 2013 COT statement on potential risks from vitamin A

The potential risks from excess iodine (2017)

External link to the national archive for the 2017 COT statement on the potentials risks from excess iodine

Addendum to the 2015 COT statement on potential risks from PBDEs in the infant diet (2017)

External link to the national archive for the 2017 Addendum to the 2015 COT statement on potential risks from polybrominated diphenyl ethers (PBDEs) in the infant diet

Potassium-based replacements for sodium chloride and sodium-based additives (2017)

External link to the national archive for the 2017 COT statement on potassium-based replacements for sodium chloride and sodium-based additives

Addendum to the 2013 COT statement on lead (2016)

External link to the national archive for the 2016 Addendum to the 2013 COT statement on lead

Potential risks from acrylamide in the diet of infants and young children (2016)

External link to the national archive for the 2016 COT Statement on Acrylamide

Statement on Arsenic in infants and young children (2016)

External link to the national archive for the 2016 COT statement on arsenic

Addendum to the 2015 COT Statement on hexabromocyclododecanes (HBCDDs) (2016)

External link to the national archive for the 2016 Addendum to the 2015 COT Statement on hexabromocyclododecanes (HBCDDs)

Polybrominated diphenyl esters (PBDEs) (2015)

External link to the national archive for the 2015 COT statement on PBDEs

Polybrominated biphenyls (PBBs) in the infant diet (2015)

External link to the national archive for the 2015 COT statement on PBBs in the infant diet

Hexabromocyclododecanes (HBCDDs) (2015)

External link to the national archive for the 2015 COT statement on HBCDDs

Domoic acid in king scallops (Pecten Maximus) (2014)

External link to the national archive for the 2014 COT statement on domoic acid in king Scallops (Pecten Maximus)

Risks from Perfluorooctane (PFOS) in the infant diet 2014

External link to the national archive for the 2014 COT statement on PFOS

Statement on Organophosphates (2014)

External link to the national archive for the 2014 COT statement on Organophosphate

Endosulfan isomers, pentachlorobenzene and chlordecone (2014)

External link to the national archive for the 2014 COT statement on endosulfan isomers, pentachlorobenzene and chlordecone

Hexachlorocyclohexanes (HCHs) (2014)

External link to the national archive for the 2014 COT statement on HCHs

The possible harmful effects of high intakes of vitamin D (2014)

External link to the national archive for the 2014 COT statement on Vitamin D

High levels of vitamin A in the infant diet (2013)

External link to the national archive for the 2013 COT on vitamin

Statement on Phytoestrogens (2013)

External link to the national archive for the 2013 COT statement on phytoestrogens

Potential risks from lead in the infant diet (2013)

External link to the national archive for the 2013 COT statement on lead

Risks of chemical toxicity and allergic disease in relation to infant diet (2012)

External link to the national archive for the 2012 COT overarching statement on risks of chemical toxicity and allergic disease in relation to infant diet

The interaction of caffeine and alcohol and their combined effects on health and behaviour (2012)

External link to the national archive for the 2012 COT Statement on the interaction of caffeine and alcohol and their combined effects on health and behaviour

Use of toxicogenomics in risk assessment (2012)

External link to the national archive for the 2012 COT statement on the use of toxicogenomics data in risk assessment

Dietary exposure to Phthalates - data from the Total Diet Study (2011)

External link to the national archive for the 2011 COT statement on dietary exposure to phthalates - data from the Total Diet Study (TDS)

Para-occupational exposure to pesticides and health outcomes (2011)

this COT statement the 2011 COT statement on para-occupational exposure to pesticides and health outcomes other than cancer

Effects of chronic dietary exposure to methanol (2011)

External link to the national archive for the 2011 COT statement on the effects of chronic dietary exposure to methanol

Proposal for restriction: DEHP, BBP, DBP DiBP (2011)

External link to the national archive for the 2011 COT summary statement on restriction report: Proposal for a restriction Bis(2-ethylhexyl)phthalate (DEHP), Benzyl butyl phthalate (BBP), Dibutyl phthalate (DBP) and Diisobutyl phthalate (DiBP)

Idiopathic Environmental Intolerance (IEI) (2011)

External link to the national archive for the 2011 COT statement on IEI

Occurrence of mixed halogenated dioxins and biphenyls in UK food (2010)

External link to the national archive for the 2010 COT statement on occurrence of mixed halogenated dioxins and biphenyls in UK food

Review of the cabin air environment, ill-health in aircraft crews and the possible relationship to smoke/fume events in aircraft (2007)

External link to the national archive for the 2007 COT statement on the review of the cabin air environment, ill-health in aircraft crews and the possible relationship to smoke/fume events in aircraft

Tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls (2001)

External link to the national archive for the 2001 COT statement on the tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls

Lead

Addendum to the 2013 COT statement on lead (2016)

External link to the national archive for the 2016 Addendum to the 2013 COT statement on lead

Potential risks from lead in the infant diet (2013)

External link to the national archive for the 2013 COT statement on lead

 

 

M

Manganese

The health effects of manganese in the diets of infants and young children (2018)

External link to the national archive for the 2018 COT statement on the health effects of manganese in the diets of infants aged 0-12 months and children aged 1-5 years

Malachite green

Surveillance for malachite green and leucomalachite green in farmed fish (1999)

External link to the national archive for the 1999 COT statement on surveillance for malachite green and leucomalachite green in farmed fish

Male reproduction

Developmental and function in adulthood of the human male reproductive system - potential chemical-induced effects (2006)

External link to the national archive for the 2006 COT meeting report on the development and function in adulthood of the human male reproductive system - potential chemical-induced effects

Male reproduction (2004)

External link to the national archive for the 2004 COT statement on male reproduction

Marine biotoxins

Risk assessment of marine biotoxins of the okadaic acid, pectenotoxin, azaspiracid and yessotoxin groups in support of human health (2006)

External link to the national archive for the 2006 COT statement on risk assessment of marine biotoxins of the okadaic acid, pectenotoxin, azaspiracid and yessotoxin groups in support of human health

Amnesic shellfish poisoning (ASP) (2001)

External link to the national archive for the 2001 COT statement on ASP

Mercury

Survey of mercury in fish and shellfish update (2004)

External link to the national archive for the 2004 updated COT statement on a survey of mercury in fish and shellfish

Survey of mercury in fish and shellfish (2003)

External link to the national archive for the 2003 COT statement on a survey of mercury in fish and shellfish

Toxicity of dental amalgam (1997)

External link to the national archive for the 1997 COT statement on the dental amalgam

Metals

The health effects of manganese in the diets of infants and young children (2018)

External link to the national archive for the 2018 COT statement on the health effects of manganese in the diets of infants aged 0-12 months and children aged 1-5 years

The results of the 2014 survey of metals and other elements in infant foods (2018)

External link to the national archive for the 2018 COT statement on the results of the 2014 survey of metals and other elements in infant foods

The potential risks from cadmium in the infant diet (2018)

External link to the national archive for the 2018 COT statement on the potential risks from cadmium

Potential risks from nickel in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on potential risks from nickel in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

Potential risks from copper in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on copper

Addendum to the 2013 COT statement on lead (2016)

External link to the national archive for the 2016 Addendum to the 2013 COT statement on lead

Addendum to the 2013 COT statement on Aluminium (2016)

External link to the national archive for the 2016 Addendum to the 2013 COT statement on Aluminium

Potential risks from aluminium in the infant diet (2013)

External link to the national archive for the 2013 COT statement on aluminium

Potential risks from lead in the infant diet (2013)

External link to the national archive for the 2013 COT statement on lead

2006 Total Diet Study - metals and other elements (2008)

External link to the national archive for the 2008 COT statement on the 2006 UK total diet study of metals and other elements

Uranium levels in water used to reconstitute infant formula (2006)

External link to the national archive for the 2006 COT statement on uranium levels in water used to reconstitute infant formula

2000 Total Diet Study - 12 metals and other elements (2004)

External link to the national archive for the 2004 COT statement on 12 metals and other elements in the 2000 Total Diet Study

Survey of mercury in fish and shellfish update (2004)

External link to the national archive for the 2004 updated COT statement on a survey of mercury in fish and shellfish

Survey of mercury in fish and shellfish (2003)

External link to the national archive for the 2003 COT statement on a survey of mercury in fish and shellfish

Metals in infant food (2003)

External link to the national archive for the 2003 COT statement on metals in infant food

Results of a multi-element survey of fungi and blackberries (2000)

External link to the national archive for the 2000 COT statement on the results of a multi-element survey of fungi and blackberries (January 2000)

Results of multi-element surveys (1998)

External link to the national archive for the 1998 COT statement on the results of multi-element surveys

Toxicity of dental amalgam (1997)

External link to the national archive for the 1997 COT statement on the toxicity of dental amalgam

Methanol

Effects of chronic dietary exposure to methanol (2011)

External link to the national archive for the 2011 COT statement on the effects of chronic dietary exposure to methanol

Methylglyoxal

Methylglyoxal (2009)

External link to the national archive for the 2009 COT statement on methylglyoxal

Methylmercury

Potential risks from methylmercury in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on methylmercury

Microbiota

Statement on interactions between xenobiotics and the human microbiota and their potential toxicological implications (2020)
Lay summary of the statement on interactions between xenobiotics and the human microbiota and their potential toxicological implications (2020)

Milk

Toxicological evaluation of chemical analyses carried out as part of a pilot study for a breast milk archive (2004)

External link to the national archive for the 2004 COT statement on a toxicological evaluation of chemical analyses carried out as part of a pilot study for a breast milk archive

Iodine in cows' milk (2000)

External link to the national archive for the 2000 COT statement on iodine in cows' milk

Iodine in cows'  milk (1997)

External link to the national archive for the 1997 COT statement on iodine in cows' milk

Health hazards of polychlorinated biphenyls (1997)

External link to the national archive for the 1997 COT statement on the health hazards of polychlorinated biphenyls

Mycotoxins

T-2 toxin (T2), HT-2 toxin (HT2) and neosolaniol (NEO) in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement of T-2 toxin (T2), HT-2 toxin (HT2) and neosolaniol (NEO) in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

The potential risks from ochratoxin A (OTA) in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on potential risks from ochratoxin A (OTA) in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

Surveillance for the mycotoxin moniliformin (1998)

External link to the national archive for the 1998 COT statement on surveillance for the mycotoxin moniliformin

Surveillance for the mycotoxin sterigmatocystin (1998)

External link to the national archive for the 1998 COT statement on surveillance for the mycotoxin sterigmatocystin

Ochratoxin A on dried vine fruits (1997)

External link to the national archive for the 1997 COT statement on ochratoxin A on dried vine fruits

 

 

N

Nanomaterial toxicology

Addendum to Joint statement on nanomaterial toxicology (2007)

External link to the national archive for the 2007 COT addendum to the joint statement of the Committees on Toxicity, Mutagenicity and Carcinogenicity on nanomaterial toxicology

Joint statement on nanomaterial toxicology (2005)

External link to the national archive for the 2005 COT joint statement on nanomaterial toxicology

New methodologies

COT workshop on 21st century toxicology (2009)

External link to the national archive for the 2009 COT statement on the COT workshop on 21st century toxicology

Joint statement of the use of toxicogenomics in toxicology in toxicology (2004)

External link to the national archive for the 2004 COT joint statement of the use of toxicogenomics in toxicology

Physiologically based pharmacokinetic modelling (2003)

External link to the national archive for the 2003 COT statement on physiologically based pharmacokinetic modelling

Symposium on the use of Genomics and Proteomics in Toxicology (2002)

External link to the national archive for the 2002 joint COT/COM/COC statement on a Symposium on the use of Genomics and Proteomics in Toxicology

Nickel

Potential risks from nickel in the diet of infants and young children (2018)

External link to the national archive for the 2018 COT statement on potential risks from nickel in the diet of infants aged 0 to 12 months and children aged 1 to 5 years

Nitrate metabolism

Nitrate metabolism in man (1999)

External link to the national archive for the 1999 COT statement on nitrate metabolism in man

 

 

P

Paralytic shellfish poisoning (PSP)

Risk assessment and monitoring of Paralytic shellfish poisoning (PSP) toxins in support of human health (2006)

External link to the national archive for the 2006 COT statement on risk assessment and monitoring of paralytic shellfish poisoning (PSP) toxins in support of human health

Parathyroid hormone axis

Phosphate and the calcium parathyroid axis (2005)

External link to the national archive for the 2005 COT statement on phosphate and the calcium parathyroid hormone axis

PAVA (Nonivamide)

TW1000, a new formulation of PAVA (2018)

External link to the national archive for the 2018 COT statement on TW1000, a new formulation of PAVA

Use of PAVA (nonivamide) as an incapacitant spray: reformulation of captor (2007)

External link to the national archive for the 2007 COT statement use of PAVA (nonivamide) as an incapacitant spray: reformulation of captor

Combined exposure to 2-Chlorobenzylidene Malonitrile (CS) and PAVA (Nonivamide) sprays (2006)

External link to the national archive for the 2006 COT statement on combined exposure to 2-Chlorobenzylidene Malonitrile (CS) and PAVA (Nonivamide) sprays

The use of PAVA (Nonivamide) as an incapacitant spray (2004)

External link to the national archive for the 2004 COT statement on the use of PAVA (Nonivamide) as an incapacitant spray

The use of PAVA (Nonivamide) as an incapacitant spray (2002)

External link to the national archive for the 2002 COT statement on the use of PAVA (Nonivamide) as an incapacitant spray

Joint statement on 2-Chlorobenzylidene Malonitrile and CS spray (1999)

External link to the national archive for the 1999 COT/COM/COC statement on 2-chlorobenzylidene malononitrile and CS spray

Peanuts

Review of the 1998 COT recommendations on peanut avoidance (2008)

External link to the national archive for the 1998 COT statement on the review of the 1998 COT recommendations on peanut avoidance

Perfluorooctane

Risks from Perfluorooctane (PFOS) in the infant diet 2014

External link to the national archive for the 2014 COT statement on perfluorooctane sulfonate (PFOS)

Tolerable daily intake for perfluorooctanoic acid (2009)

External link to the national archive for the 2009 COT statement on the tolerable daily intake for perfluorooctanoic acid

Tolerable daily intake for perfluorooctanoic sulfonate (2006)

External link to the national archive for the 2006 COT statement on the tolerable daily intake for perfluorooctane sulfonate

Tolerable daily intake for perfluorooctanoic acid (2006)

External link to the national archive for the 2006 COT statement on the tolerable daily intake for perfluorooctanoic acid

Pesticides

FSA-funded research and other progress on mixtures of pesticides and similar substances (2011)

External link to the national archive for the 2011 COT statement on FSA-funded research and other progress on mixtures of pesticides and similar substances

Para-occupational exposure to pesticides and health outcomes (2011)

External link to the national archive for the 2011 COT statement on para-occupational exposure to pesticides and health outcomes other than cancer

Phthalates

Dietary exposure to Phthalates - data from the Total Diet Study (2011)

External link to the national archive for the 2011 COT statement on dietary exposure to phthalates - data from the Total Diet Study (TDS)

Phthalates in infant formulae (1996)

External link to the national archive for the 1996 COT statement on phthalates in infant formulae

Pharmacokinetic modelling

Physiologically based pharmacokinetic modelling (2003)

External link to the national archive for the 2003 COT statement on physiologically based pharmacokinetic modelling

Phenol

Phenol: tolerable daily intake (oral) (2002)

External link to the national archive for the 2002 COT statement on phenol: tolerable daily intake (oral) - October 2002

Phosphate

Phosphate-based flame retardants and the potential for neurodevelopmental toxicity (2019)

COT statement on phosphate-based flame retardants and the potential for neurodevelopmental toxicity

Phytoestrogens

The effects of soya phytoestrogen consumption on thyroid status (2015)

External link to the national archive for the 2015 COT statement on the effects of soya phytoestrogen consumption on thyroid status

Statement on Phytoestrogens (2013)

External link to the national archive for the 2013 COT statement on Phytoestrogens

Phytoestrogens research programme (2012)

External link to the national archive for the 2012 COT statement on the FSA phytoestrogens research programme

Phytoestrogens (1996)

External link to the national archive for the 1996 COT statement on phytoestrogens

Pine bark

Supplements containing French maritime pine bark extracts (1999)

External link to the national archive for the 1999 COT statement on supplements containing french maritime pine bark extracts

Polybrominated biphenyls (PBBs) in the infant diet

Polybrominated biphenyls (PBBs) in the infant diet (2015)

External link to the national archive for the 2015 COT statement on polybrominated biphenyls (PBBs) in the infant diet

Polybrominated diphenyl ethers (PBDEs)

Addendum to the 2015 COT statement on potential risks from PBDEs in the infant diet (2017)

External link to the national archive for the 2017 Addendum to the 2015 COT statement on potential risks from polybrominated diphenyl ethers (PBDEs) in the infant diet

Polybrominated diphenyl esters (PBDEs) (2015)

External link to the national archive for the 2015 COT statement on polybrominated diphenyl ethers (PBDEs)

Polycyclic Aromatic Hydrocarbons (PAHs)

Polycyclic Aromatic Hydrocarbons - interim pragmatic guideline limits for use in emergencies (2001)

External link to the national archive for the 2001 COT statement on Polycyclic Aromatic Hydrocarbons - interim pragmatic guideline limits for use in emergencies - March 2001

Polychlorinated dibenzo-p-dioxins (PCDDs), Polychlorinated dibenzofurans (PCDFs) and Polychlorinated biphenyls (PCBs)

Polychlorinated naphthalenes in food (2009)

External link to the national archive for the 2009 COT statement polychlorinated naphthalenes in food

Tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls (2001)

External link to the national archive for the 2001 COT statement on the tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls

Dietary exposure to dioxins and dioxin-like PCBs (2000)

External link to the national archive for the 2000 COT statement on dietary exposure to dioxins and dioxin-like PCBs (August 2000)

Dioxins and dioxin-like PCBs in free-range eggs (2000)

External link to the national archive for the 2000 COT statement on dioxins and dioxin-like PCBs in free-range eggs (June 2000)

Results of a survey for PCDDs, PCDFs and PCBs in Marine Fish and Fish Products (1999)

External link to the national archive for the 1999 COT statement on the results of a survey for PCDDs, PCDFs and PCBs in Marine Fish and Fish Products

Health hazards of polychlorinated biphenyls (1997)

External link to the national archive for the 1997 COT statement on the health hazards of polychlorinated biphenyls (April 1997)

Potassium

Potassium-based replacements for sodium chloride and sodium-based additives (2017)

External link to the national archive for the 2017 COT statement on potassium-based replacements for sodium chloride and sodium-based additives

Potassium position paper (2014)

External link to the national archive for the 2014 COT position paper on potassium

Pyrrolizidine Alkaloids

Pyrrolizidine Alkaloids in Food (2008)

External link to the national archive for the 2008 COT statement on pyrrolizidine alkaloids in food

 

 

Q

No statements yet

 

 

R

Reproduction

Developmental and function in adulthood of the human male reproductive system - potential chemical-induced effects (2006)

External link to the national archive for the 2006 COT meeting report on the development and function in adulthood of the human male reproductive system - potential chemical-induced effects

Male reproduction (2004)

External link to the national archive for the 2004 COT statement on male reproduction

Chlorinated water and reproductive outcomes (2004)

External link to the national archive for the 2004 COT statement on chlorinated water and reproductive outcomes

Reproductive effects of caffeine (2001)

External link to the national archive for the 2001 COT statement on the reproductive effects of caffeine

Chlorinated water and reproductive outcomes (1999)

External link to the national archive for the 1999 COT statement on chlorinated water and reproductive outcomes

Tetrachloroethylene and the reproductive health of workers in the dry-cleaning industry (1997)

External link to the national archive for the 1997 COT statement on tetrachloroethylene and the reproductive health of workers in the dry-cleaning industry (November 1997)

 

Risk assessment

COT workshop on evolving approaches to chemical risk assessment (2007)

External link to the national archive for the 2007 COT statement on the COT workshop on evolving approaches to chemical risk assessment

Risk assessment of marine biotoxins of the okadaic acid, pectenotoxin, azaspiracid and yessotoxin groups in support of human health (2006)

External link to the national archive for the 2006 COT statement on risk assessment of marine biotoxins of the okadaic acid, pectenotoxin, azaspiracid and yessotoxin groups in support of human health

Risk assessment and monitoring of Paralytic shellfish poisoning (PSP) toxins in support of human health (2006)

External link to the national archive for the 2006 COT statement on risk assessment and monitoring of paralytic shellfish poisoning (PSP) toxins in support of human health

 

 

S

Salatrims / Structured triglycerides

Consideration of toxicological data for some structural triglycerides (Salatrims) composed of mixtures of short and long chain fatty acids (2000)

External link to the national archive for the 2000 COT statement on a consideration of toxicological data for some structured triglycerides composed of mixtures of short and long chain fatty acids

Toxicological aspects of submission on Salatrims, for ACNFP (1999)

External link to the national archive for the 1999 COT statement for the Advisory Committee on Novel Foods and Processes on toxicological aspects of a submission on Salatrims

Salatrims for ACNFP (1997)

External link to the national archive for the 1997 COT statement for the Advisory Committee on Novel Foods and Processes on Salatrims

Shellfish

Domoic acid in king scallops (Pecten Maximus) (2014)

External link to the national archive for the 2014 COT statement on domoic acid in king Scallops (Pecten Maximus)

Organic chlorinated and brominated contaminants in shellfish, farmed and wild fish (2006)

External link to the national archive for the 2006 COT statement on organic chlorinated and brominated contaminants in shellfish, farmed and wild fish

Risk assessment of marine biotoxins of the okadaic acid, pectenotoxin, azaspiracid and yessotoxin groups in support of human health (2006)

External link to the national archive for the 2006 COT statement on risk assessment of marine biotoxins of the okadaic acid, pectenotoxin, azaspiracid and yessotoxin groups in support of human health

Risk assessment and monitoring of Paralytic shellfish poisoning (PSP) toxins in support of human health (2006)

External link to the national archive for the 2006 COT statement on risk assessment and monitoring of paralytic shellfish poisoning (PSP) toxins in support of human health

Brominated flame retardants in fish from the Skerne-Tees rivers system (2004)

External link to the national archive for the 2004 COT statement on brominated flame retardants in fish from the Skerne-Tees rivers system

Survey of mercury in fish and shellfish update (2004)

External link to the national archive for the 2004 updated COT statement on a survey of mercury in fish and shellfish

Survey of mercury in fish and shellfish (2003)

External link to the national archive for the 2003 COT statement on a survey of mercury in fish and shellfish

Amnesic shellfish poisoning (2001)

External link to the national archive for the 2001 COT statement on ASP

Soya

The effects of soya phytoestrogen consumption on thyroid status (2015)

External link to the national archive for the 2015 COT statement on the effects of soya phytoestrogen consumption on thyroid status

Statement on Phytoestrogens (2013)

External link to the national archive for the 2013 COT statement on Phytoestrogens

Sterigmatocystin

Results of a survey for Sterigmatocystin in foodstuffs (2000) 

External link to the national archive for the 2000 COT statement on the results of a survey for Sterigmatocystin in foodstuffs (February 2000)

Surveillance for the mycotoxin sterigmatocystin (1998)

External link to the national archive for the 1998 COT statement on surveillance for the mycotoxin sterigmatocystin

Supplements

Addendum to the 2013 COT statement on potential risks from vitamin A (2017)

External link to the national archive for the 2017 Addendum to the 2013 COT statement on potential risks from vitamin A

The possible harmful effects of high intakes of vitamin D (2014)

External link to the national archive for the 2014 COT statement on Vitamin D

High levels of vitamin A in the infant diet (2013)

External link to the national archive for the 2013 COT statement on Vitamin A

Supplements containing French maritime pine bark extracts (1999)

External link to the national archive for the 1999 COT statement on supplements containing french maritime pine bark extracts

Preliminary observations on the US NAS report on a tolerable upper intake level for vitamin B6 (1998)

External link to the national archive for the 1998 COT statement on preliminary observations on the US NAS report on a tolerable upper intake level for vitamin B6

Vitamin B6 (pyridoxine) toxicity (1997)

External link to the national archive for the 1997 COT statement on vitamin B6 (pyridoxine) toxicity (June 1997)

 

 

T

Terephthalic acid

Toxicology of Terephthalic acid (2008)

External link to the national archive for the 2008 COT updated statement on the toxicology of terephthalic acid

Terephthalic and Isophthalic Acids from can coatings (2000)

External link to the national archive for the 2000 COT statement on Terephthalic And Isophthalic Acids From Can Coatings (September 2000)

Tetrabromobisphenol A

Tetrabromobisphenol A - review of toxicological data (2004)

External link to the national archive for the 2004 COT statement on tetrabromobisphenol A - review of toxicological data

Tetrachloroethylene

Tetrachloroethylene and the reproductive health of workers in the dry-cleaning industry (1997)

External link to the national archive for the 1997 COT statement on tetrachloroethylene and the reproductive health of workers in the dry-cleaning industry (November 1997)

Tobacco

Heat not burn tobacco products (2017)

External link to the national archive for the 2017 COT statement on heat not burn tobacco products

Re - assessment of the toxicological testing of tobacco (2004)

External link to the national archive for the 2004 joint COT statement on the re-assessment of the toxicological testing of tobacco

Total diet study

2006 Total Diet Study - metals and other elements (2008)

External link to the national archive for the 2008 COT statement on the 2006 UK total diet study of metals and other elements

2000 Total Diet Study - 12 metals and other elements (2004)

External link to the national archive for the 2004 COT statement on 12 metals and other elements in the 2000 Total Diet Study

Arsenic in food: results of the 1999 total diet study (2003)

External link to the national archive for the 2003 COT statement on arsenic in food: results of the 1999 total diet study

COT statement on fluorine in the 1997 total diet study (2003)

External link to the national archive for the 2003 COT statement on fluorine in the 1997 total diet study

The 1997 Total Diet Study - Fluorine, Bromine, and Iodine (2000)

External link to the national archive for the 2000 COT statement on the 1997 Total Diet Study - Fluorine, Bromine, and Iodine (July 2000)

Tryptophan

Tryptophan And The Eosinophilia-Myalgia Syndrome (2004)

External link to the national archive for the 2004 COT statement On Tryptophan And The Eosinophilia-Myalgia Syndrome

 

 

V

Vitamin A

Addendum to the 2013 COT statement on potential risks from vitamin A (2017)

External link to the national archive for the 2017 Addendum to the 2013 COT statement on potential risks from vitamin A

High levels of vitamin A in the infant diet (2013)

External link to the national archive for the 2013 COT statement on Vitamin A

Vitamin B6

Preliminary observations on the US NAS report on a tolerable upper intake level for vitamin B6 (1998)

External link to the national archive for the 1998 COT statement on preliminary observations on the US NAS report on a tolerable upper intake level for vitamin B6

Vitamin B6 (pyridoxine) toxicity (1997)

External link to the national archive for the 1997 COT statement on vitamin B6 (pyridoxine) toxicity (June 1997)

Vitamin D

The possible harmful effects of high intakes of vitamin D (2014)

External link to the national archive for the 2014 COT statement on Vitamin D

 

 

X

No statements yet

 

 

Y

No statements yet

 

 

Z

No statements yet