More in this section
The Committee has been asked by the Home Office Science Development Branch (HOSDB) for advice on the potential effects of exposure to both 2-chlorobenzylidene malonitrile (CS) and pelargonic acid vanillylamide (PAVA).
The COT and COC were asked by Defra and the ACP to comment on the RCEP report.
The Committee considered further toxicity studies in the rat of a hydrogel filler for breast implants.
The Food Standards Agency became aware that bitter apricot kernels containing high levels of amygdalin, a cyanogenic glycoside, were on sale as a health food. The COT were asked to review the available data and, if possible, to establish a maximum upper level for the safe intake of cyanide or cyanogenic substances.
The COT previously assessed the safety of DEET in 2003 and at that time made a recommendation that the literature on DEET should be regularly reviewed.
The COT has reviewed recent studies on the chemical safety of uranium because there have been concerns over uranium in natural mineral water and other bottled waters for the preparation of infant feed.
The Food Standards Agency commissioned analysis of the 2004 Total Diet Study samples for perfluorooctanoic acid (PFOA) and the Committee was invited to consider the toxicology of PFOA and the results of the analysis.
The Food Standards Agency commissioned analysis of the 2004 Total Diet Study samples for perfluorooctane sulfonate (PFOS) and the Committee was invited to consider the toxicology of PFOS and the results of the analysis.
The Committee was asked for its views on the risk assessment of a range of biotoxins that can occur in shellfish in order to support protection of consumer health.
The Committee was asked for its view on the risk assessment of PSP toxins, and on the best method(s) of testing for biotoxins responsible for PSP in order to support protection of the health of the consumer.
The Food Standards Agency completed two surveys of a range of fish species consumed in the UK. The COT reviewed the toxicological properties of the organic contaminants and considered whether the survey results formed a basis for the Agency to amend its current advice on fish consumption. It decided that, based on these surveys, the Agency did not need to change its advice on oily fish.
The COT and the Committee on the Safety of Medicines held a joint meeting on the 2nd February 2005 to consider the issue of interactions between drugs and the diet. A range of topics covering many aspects of the subjects was considered. Information from the talks and subsequent discussions is summarised in the following statement.
The COT has reviewed possible effects of a range of food additives on the developing nervous system, because there have been recent developments in the toxicological approaches in this area.
The Food Standards Agency received the results of a study, investigating the occurrence and formation of disinfectants and disinfection by-products in prepared salads. The study involved analysing a range of prepared salads, bought from various shops. The COT concluded that the study results did not indicate any cause for concern with respect to the use of chlorine washes.
The COT has reviewed the recent WHO re-evaluation of the Toxic Equivalency Factors (TEFs) for comparing the potency of dioxins and dioxin-like chemicals. The COT agreed with the scientific rationale used in the re-evaluation and concluded that these re-evaluated TEF values should be used in future UK risk assessments of dioxins and dioxin-like chemicals.
The COT held a meeting on 15 February 2006 to consider evidence produced since the COT last evaluated the subject in 2004 of potential chemical-induced effects on the development and function in adulthood of the human male reproductive system. Information from the presentations and subsequent COT discussions is summarised in this meeting report.