COT statement on nitrate metabolism in man

The COT has considered a report on the results of research into the human metabolism of nitrate in the form of ionic salts or incorporated into lettuce.

It considered that the research was a relevant contribution to the study of nitrate metabolism. However, it had reservations about the suggested role of nitric oxide, a metabolite of ingested nitrate, in altering immunological and physiological responses and considered that the data would not influence the Acceptable Daily Intake for nitrate and nitrite. Its conclusions and the report have been submitted to the European Commission and the Scientific Committee on Food.